Skip to main content
Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 1996;74(1):85–90.

Mass administration of DEC-medicated salt for filariasis control in the endemic population of Karaikal, south India: implementation and impact assessment.

G S Reddy 1, N Venkateswaralu 1
PMCID: PMC2486855  PMID: 8653820

Abstract

DEC (diethylcarbamazine)-medicated salt, at a concentration of 0.1 to 0.2 mg per 100 mg, was given to the entire population of Karaikal (119 978) in South India for a 4-year period from 1982. The per capita consumption of DEC in medicated salt was 13.3 grams for the entire period. The prevalence of microfilaraemia declined significantly from 4.5% in 1982 to 0.14% in 1985 and 0.4% in 1993. Vector infection declined from 0.6% in 1982 to zero after two years. The mechanism of preparation and regulated distribution of DEC-medicated salt in the locality is presented. Long-term follow-up suggests that DEC-medicated salt distribution is cheap, safe and efficient for the elimination of filariasis.

Full text

PDF
85

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Fan P. C. Filariasis eradication on Kinmen Proper, Kinmen (Quemoy) Islands, Republic of China. Acta Trop. 1990 Mar;47(3):161–169. doi: 10.1016/0001-706x(90)90022-r. [DOI] [PubMed] [Google Scholar]
  2. Gelband H. Diethylcarbamazine salt in the control of lymphatic filariasis. Am J Trop Med Hyg. 1994 Jun;50(6):655–662. doi: 10.4269/ajtmh.1994.50.655. [DOI] [PubMed] [Google Scholar]
  3. Hawking F., Marques R. J. Control of Bancroftian filariasis by cooking salt medicated with diethylcarbamazine. Bull World Health Organ. 1967;37(3):405–414. [PMC free article] [PubMed] [Google Scholar]
  4. Krishnamoorthy K., Sabesan S., Panicker K. N., Prathiba J. Daily diethylcarbamazine for the treatment of Brugia malayi microfilaria carriers. Natl Med J India. 1992 May-Jun;5(3):104–107. [PubMed] [Google Scholar]
  5. Narasimham M. V., Sharma S. P., Sundaram R. M., Reddy G. S., Raina V. K., Sambasivam V., Das M. Control of bancroftian filariasis by diethylcarbamazine medicated common salt in Karaikal, Pondicherry, India. J Commun Dis. 1989 Sep;21(3):157–170. [PubMed] [Google Scholar]
  6. Ottesen E. A. Efficacy of diethylcarbamazine in eradicating infection with lymphatic-dwelling filariae in humans. Rev Infect Dis. 1985 May-Jun;7(3):341–356. doi: 10.1093/clinids/7.3.341. [DOI] [PubMed] [Google Scholar]
  7. Panicker K. N., Krishnamoorthy K., Sabesan S., Prathiba J., Abidha Comparison of effects of mass annual and biannual single dose therapy with diethylcarbamazine for the control of Malayan filariasis. Southeast Asian J Trop Med Public Health. 1991 Sep;22(3):402–411. [PubMed] [Google Scholar]
  8. Ramaiah K. D., Pani S. P., Balakrishnan N., Sadanandane C., Das L. K., Mariappan T., Rajavel A. R., Vanamail P., Subramanian S. Prevalence of bancroftian filariasis & its control by single course of diethyl carbamazine in a rural area in Tamil Nadu. Indian J Med Res. 1989 May;89:184–191. [PubMed] [Google Scholar]
  9. Rao P. K., Venkatanarayana M., Narasimham M. V., Rao C. K. Effect of diethylcarbamazine medicated common salt on Wuchereria bancrofti prophylaxis. J Commun Dis. 1980 Dec;12(4):205–209. [PubMed] [Google Scholar]
  10. Sen A. B., Chandra R., Katiyar J. C., Chandra S. Diethylcarbamazine medicated salt in the chemotherapeutic control of filariasis due to Wuchereria bancrofti in an open community. Indian J Med Res. 1974 Aug;62(8):1181–1189. [PubMed] [Google Scholar]
  11. Vanamail P., Subramanian S., Das P. K., Pani S. P., Rajagopalan P. K., Bundy D. A., Grenfell B. T. Estimation of age-specific rates of acquisition and loss of Wuchereria bancrofti infection. Trans R Soc Trop Med Hyg. 1989 Sep-Oct;83(5):689–693. doi: 10.1016/0035-9203(89)90399-4. [DOI] [PubMed] [Google Scholar]

Articles from Bulletin of the World Health Organization are provided here courtesy of World Health Organization

RESOURCES