Skip to main content
NCBI home page
Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 1986;64(1):101–105.

An international study on the serological differential diagnosis of human cystic and alveolar echinococcocis

Bruno Gottstein, Peter M Schantz, Todor Todorov, Adrien G Saimot, Patrick Jacquier
PMCID: PMC2490924  PMID: 3488132

Abstract

An enzyme-linked immunosorbent assay (ELISA) for the serological differentiation of cystic (Echinococcus granulosus) and alveolar (E. multilocularis) echinococcosis in man has been evaluated. A discrimination rate of 95.1% was found for 82 sera from patients of geographically disparate endemic areas. This rate was essentially the same as that found for 57 Swiss patients, indicating that inter- and intraspecific strain differences do not influence the test results. The assay method is suitable for immunodiagnostic purposes as well as for seroepidemiological studies.

Full text

PDF
101

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Gottstein B., Eckert J., Fey H. Serological differentiation between Echinococcus granulosus and E. multilocularis infections in man. Z Parasitenkd. 1983;69(3):347–356. doi: 10.1007/BF00927876. [DOI] [PubMed] [Google Scholar]
  2. Gottstein B. Purification and characterization of a specific antigen from Echinococcus multilocularis. Parasite Immunol. 1985 May;7(3):201–212. doi: 10.1111/j.1365-3024.1985.tb00070.x. [DOI] [PubMed] [Google Scholar]
  3. Grabbe E., Kern P., Heller M. Human echinococcosis: diagnostic value of computed tomography. Tropenmed Parasitol. 1981 Mar;32(1):35–38. [PubMed] [Google Scholar]
  4. McManus D. P. A biochemical study of adult and cystic stages of Echinococcus granulosus of human and animal origin from Kenya. J Helminthol. 1981 Mar;55(1):21–27. [PubMed] [Google Scholar]
  5. Pandolfo I., Blandino G., Scribano E., Longo M., Certo A., Chirico G. CT findings in hepatic involvement by Echinococcus granulosus. J Comput Assist Tomogr. 1984 Oct;8(5):839–845. doi: 10.1097/00004728-198410000-00005. [DOI] [PubMed] [Google Scholar]
  6. Smyth J. D., Davies Z. Occurrence of physiological strains of Echinococcus granulosus demonstrated by in vitro culture of protoscoleces from sheep and horse hydatid cysts. Int J Parasitol. 1974 Aug;4(4):443–445. doi: 10.1016/0020-7519(74)90057-5. [DOI] [PubMed] [Google Scholar]
  7. Thompson R. C., Kumaratilake L. M., Eckert J. Observations on Echinococcus granulosus of cattle origin in Switzerland. Int J Parasitol. 1984 Jun;14(3):283–291. doi: 10.1016/0020-7519(84)90079-1. [DOI] [PubMed] [Google Scholar]

Articles from Bulletin of the World Health Organization are provided here courtesy of World Health Organization

RESOURCES