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Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 1989;67(4):449–450.

Nomenclature of the Fc receptors. IUIS subcommittee on nomenclature.

PMCID: PMC2491266  PMID: 2805222

Abstract

Fc receptors (FcR) that are specific for particular immunoglobulin isotypes are designated by Greek letters. Subtypes of receptors are denoted by capital Roman numerals, such as: Fc gamma RI, II and III: Fc receptors for IgG on macrophages/monocytes and lymphocytes (numerals are in the order of affinity for IgG); Fc alpha R, Fc mu R and Fc delta R: Fc receptors for IgA, IgM and IgD; Fc epsilon RI: high-affinity receptors for IgE on mast cells and basophils; Fc epsilon RII: low-affinity receptors for IgE on lymphocytes, macrophages, and activated eosinophils. Species are abbreviated as follows: hu (human), mo (mouse), rt (rat), and rb (rabbit). Subunits of receptors are designated by Greek letters alpha, beta, gamma and transcripts by a, b, c, etc. Ig-BF describes the soluble molecules having affinity for immunoglobulin.

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