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. 1990 May;64(5):2411–2415. doi: 10.1128/jvi.64.5.2411-2415.1990

Promoter evolution in BK virus: functional elements are created at sequence junctions.

R B Markowitz 1, S Tolbert 1, W S Dynan 1
PMCID: PMC249406  PMID: 2157897

Abstract

The archetypal strain of BK virus directed very little early gene expression compared with rearranged laboratory strains of the virus. One laboratory strain that was analyzed in detail contained newly created AP-1 binding enhancer modules spanning the junction between adjacent sequence repeats. Introduction of these sequences into the archetype activated the previously quiescent early promoter.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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