Abstract
Systemic prophylactic antibiotics to prevent Streptococcus pyogenes infections in newly burnt patients have been recommended for many years. However, a review of patients admitted to one Regional Burns Centre shows only a small percentage develop such infections, even if no systemic prophylaxis is used. Other Centres have reported similar results. Possible uses of systemic prophylactic antibiotics in patients with burns are reviewed. It is suggested that these antibiotics are restricted to a small minority of patients to prevent peri-operative septicaemia and gas-gangrene.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Barber H. R. Symposium on gynecologic cancer: foreword. Surg Clin North Am. 1978 Feb;58(1):1–2. [PubMed] [Google Scholar]
- CASON J. S., LOWBURY E. J. Prophylactic chemotherapy for burns. Studies on the local and systemic use of combined therapy. Lancet. 1960 Sep 3;2(7149):501–507. doi: 10.1016/s0140-6736(60)91539-7. [DOI] [PubMed] [Google Scholar]
- Lilly H. A., Lowbury E. J. Antibiotic resistance of Staphylococcus aureus in a burns unit after stopping routine prophylaxis with erythromycin. J Antimicrob Chemother. 1978 Nov;4(6):545–550. doi: 10.1093/jac/4.6.545. [DOI] [PubMed] [Google Scholar]
- Pruitt B. A., Jr The burn patient: I. Initial care. Curr Probl Surg. 1979 Apr;16(4):1–55. doi: 10.1016/s0011-3840(79)80006-4. [DOI] [PubMed] [Google Scholar]
- Smith J. W., Laurence D. R., Evans D. G. Prevention of tetanus in the wounded. Br Med J. 1975 Aug 23;3(5981):453–455. doi: 10.1136/bmj.3.5981.453. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WALLACE A. B. Treatment of burns; a return to basic principles. Br J Plast Surg. 1949 Jan;1(4):232–244. [PubMed] [Google Scholar]
- Wilkins T. J., Bennett J. E. The selective use of systemic antibiotics in the treatment of burns. Surg Gynecol Obstet. 1980 Sep;151(3):404–406. [PubMed] [Google Scholar]
