Abstract
We report a 91% accuracy with fine needle aspiration cytology in 46 patients found to have a mass in the pancreas at laparotomy. Results were compared with conventional biopsy at operation which was accurate in only 56% of an earlier group of 48 patients with a localised mass compared with 97% in 33 patients with disseminated malignancy. Although we strongly advise a through attempt to establish a histological or cytological diagnosis before operation, there are many occasions when a surgeon is faced with an undiagnosed mass in the pancreas at laparotomy. Under these circumstances fine needle aspiration cytology of the pancreas should be advised in units with an experienced cytology service.
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- ACKERMAN L. V., RAMIREZ G. A. The indications for and limitations of frozen section diagnosis; a review of 1269 consecutive frozen section diagnoses. Br J Surg. 1959 Jan;46(198):336–350. doi: 10.1002/bjs.18004619806. [DOI] [PubMed] [Google Scholar]
- BOWDEN L. The fallibility of pancreatic biopsy. Ann Surg. 1954 Apr;139(4):403–408. doi: 10.1097/00000658-195404000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brits C. J., Franz R. C. Pale nodular nuclei-diagnostic of adenocarcinoma of the pancreas? Acta Cytol. 1976 Sep-Oct;20(5):462–468. [PubMed] [Google Scholar]
- Forsgren L., Orell S. Aspiration cytology in carcinoma of the pancreas. Surgery. 1973 Jan;73(1):38–42. [PubMed] [Google Scholar]
- George P., Brown C., Gilchrist J. Operative biopsy of the pancreas. Br J Surg. 1975 Apr;62(4):280–283. doi: 10.1002/bjs.1800620407. [DOI] [PubMed] [Google Scholar]
- Hatfield A. R., Smithies A., Wilkins R., Levi A. J. Assessment of endoscopic retrograde cholangio-pancreatography (ERCP) and pure pancreatic juice cytology in patients with pancreatic disease. Gut. 1976 Jan;17(1):14–21. doi: 10.1136/gut.17.1.14. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hovdenak N., Lees W. R., Pereira J., Beilby J. O., Cotton P. B. Ultrasound-guided percutaneous fine-needle aspiration cytology in pancreatic cancer. Br Med J (Clin Res Ed) 1982 Oct 23;285(6349):1183–1184. doi: 10.1136/bmj.285.6349.1183. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kameya S., Kuno N., Kasugai T. The diagnosis of pancreatic cancer by pancreatic juice cytology. Acta Cytol. 1981 Jul-Aug;25(4):354–360. [PubMed] [Google Scholar]
- Kolins M. D., Bernacki E. G., Jr, Schwab R. Diagnosis of pancreatic lesions by percutaneous aspiration biopsy. Acta Cytol. 1981 Nov-Dec;25(6):675–677. [PubMed] [Google Scholar]
- Lightwood R., Reber H. A., Way L. W. The risk and accuracy of pancreatic biopsy. Am J Surg. 1976 Aug;132(2):189–194. doi: 10.1016/0002-9610(76)90046-5. [DOI] [PubMed] [Google Scholar]
- Reuben A. Operative pancreatic biopsy: a survey of current practice. Ann R Coll Surg Engl. 1978 Jan;60(1):53–57. [PMC free article] [PubMed] [Google Scholar]
- Shorey B. A. Aspiration biopsy of carcinoma of the pancreas. Gut. 1975 Aug;16(8):645–647. doi: 10.1136/gut.16.8.645. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Simms M. H., Tindall N., Allan R. N. Pancreatic fistula following operative fine-needle aspiration. Br J Surg. 1982 Sep;69(9):548–548. doi: 10.1002/bjs.1800690917. [DOI] [PubMed] [Google Scholar]
- Smithies A., Hatfield A. R., Brown B. E. The cytodiagnostic aspects of pure pancreatic juice obtained at the time of endoscopic retrograde cholangio-pancreatography (E.R.C.P.) Acta Cytol. 1977 Mar-Apr;21(2):191–195. [PubMed] [Google Scholar]
- Winegarner F. G., Hague W. H., Elliott D. W. Tissue diagnosis and surgical management of malignant jaundice. Am J Surg. 1966 Jan;111(1):5–7. doi: 10.1016/0002-9610(66)90336-9. [DOI] [PubMed] [Google Scholar]