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. 1972 Jul;48(561):417–421. doi: 10.1136/pgmj.48.561.417

Six cases of poisoning after a parenteral organic mercurial compound (Merthiolate)

J H M Axton
PMCID: PMC2495252  PMID: 5069897

Abstract

The case histories of four children and two adults who were accidentally given toxic amounts of Merthiolate are recorded. The possible modes of action of Merthiolate in causing symptoms are discussed.

Five out of the six patients died, and necropsy showed extensive renal tubular necrosis in each case, and in two, evidence of diffuse intravascular coagulation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. FRIBERG L., ODEBLAD E., FORSSMAN S. Distribution of two mercury compounds in rabbits after a single subcutaneous injection; a radiometric and autoradiographic study of the distribution of mercuric chloride and phenylmercuric acetate. AMA Arch Ind Health. 1957 Aug;16(2):163–168. [PubMed] [Google Scholar]
  2. KURLAND L. T., FARO S. N., SIEDLER H. Minamata disease. The outbreak of a neurologic disorder in Minamata, Japan, and its relationship to the ingestion of seafood contaminated by mercuric compounds. World Neurol. 1960 Nov;1:370–395. [PubMed] [Google Scholar]
  3. LADD A. C., GOLDWATER L. J., JACOBS M. B. ABSORPTION AND EXCRETION OF MERCURY IN MAN. V. TOXICITY OF PHENYLMERCURIALS. Arch Environ Health. 1964 Jul;9:43–52. doi: 10.1080/00039896.1964.10663791. [DOI] [PubMed] [Google Scholar]
  4. MILLER V. L., KLAVANO P. A., CSONKA E. Absorption, distribution and excretion of phenylmercuric acetate. Toxicol Appl Pharmacol. 1960 May;2:344–352. doi: 10.1016/0041-008x(60)90063-6. [DOI] [PubMed] [Google Scholar]

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