Skip to main content
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 1973 Apr;49(570):255–257. doi: 10.1136/pgmj.49.570.255

Pregnancy and the skeletal complications of sickle cell disease

Oladele Akinla
PMCID: PMC2495689  PMID: 4796827

Abstract

An account is given of three patients with the skeletal complications of sickle cell disease in association with pregnancy. Avascular necrosis of bone and acute osteomyelitis are the usual forms of these complications.

The associated high perinatal mortality is probably due to the constant hypoxia to which the foetus is exposed during both pregnancy and labour.

Full text

PDF
255

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. HOOK E. W., CAMPBELL C. G., WEENS H. S., COOPER G. R. Salmonella osteomyelitis in patients with sickle-cell anemia. N Engl J Med. 1957 Aug 29;257(9):403–407. doi: 10.1056/NEJM195708292570904. [DOI] [PubMed] [Google Scholar]
  2. Hendrickse J. P., Watson-Williams E. J. The influence of hemoglobinopathies on reproduction. Am J Obstet Gynecol. 1966 Mar 1;94(5):739–748. doi: 10.1016/0002-9378(66)90406-6. [DOI] [PubMed] [Google Scholar]
  3. MCCURDY P. R. ABNORMAL HEMOGLOBINS AND PREGNANCY. Am J Obstet Gynecol. 1964 Dec 1;90:891–896. doi: 10.1016/0002-9378(64)90783-5. [DOI] [PubMed] [Google Scholar]
  4. ROBERTS A. R., HILBURG L. E. Sickle cell disease with Salmonella osteomyelitis. J Pediatr. 1958 Feb;52(2):170–175. doi: 10.1016/s0022-3476(58)80089-x. [DOI] [PubMed] [Google Scholar]
  5. SILVER H. K., SIMON J. L., CLEMENT D. H. Salmonella osteomyelitis and abnormal hemoglobin disease. Pediatrics. 1957 Sep;20(3):439–447. [PubMed] [Google Scholar]
  6. WIDEN A. L., CARDON L. Salmonella typhimurium osteomyelitis with sickle cell-hemoglobin C disease: a review and case report. Ann Intern Med. 1961 Mar;54:510–521. doi: 10.7326/0003-4819-54-3-510. [DOI] [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES