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. 1990 Jul;64(7):3509–3515. doi: 10.1128/jvi.64.7.3509-3515.1990

Expression of collagenlike sequences by a tumor virus, herpesvirus saimiri.

P Geck 1, S A Whitaker 1, M M Medveczky 1, P G Medveczky 1
PMCID: PMC249618  PMID: 2161952

Abstract

Sequencing demonstrates that the oncogenic regions of a group A strain and a group C strain of herpesvirus saimiri are nonhomologous. A bicistronic viral mRNA from this region is transcribed in tumor cells transformed by a highly oncogenic group C virus. The first open reading frame is homologous to collagen; no such sequences were found in group A or B strains. This is the first report that a virus encodes for sequences similar to those of a connective tissue protein.

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Selected References

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