Skip to main content
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 1976 Aug;52(610):497–500. doi: 10.1136/pgmj.52.610.497

Pneumococcal antigen in pneumonia. A post-mortem study with the histological and bacteriological findings.

M El-Refaie, R Tait, C Dulake, F E Dische
PMCID: PMC2496452  PMID: 10565

Abstract

Pneumococcal capsular antigens can be detected in lung tissue by counter-current immunoelectrophoresis even when, following antibiotics, post-mortem bacterilogy suggests that Escherichia coli has replaced pneumococci. The results suggest that antipneumococcal therapy would benefit at least 55% of patients critically ill with lung infection and that the potentially toxic drugs directed at coliform bacteria may be unnecessary.

Full text

PDF
497

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. El-Refaie M., Dulake C. Counter-current immunoelectrophoresis for the diagnosis of pneumococcal chest infection. J Clin Pathol. 1975 Oct;28(10):801–806. doi: 10.1136/jcp.28.10.801. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Foster W. D. The bacteriology of necrotizing jejunitis in Uganda. East Afr Med J. 1966 Nov;43(11):550–553. [PubMed] [Google Scholar]
  3. GRIST N. R., LANDSMAN J. B., ANDERSON T., ROWAN G., SMITH A. Studies in the aetiology of pneumonia in Glasgow, 1950-51. Lancet. 1952 Mar 29;1(6709):640–646. doi: 10.1016/s0140-6736(52)90160-8. [DOI] [PubMed] [Google Scholar]
  4. KNEELAND Y., Jr, PRICE K. M. Antibiotics and terminal pneumonia. A postmortem microbiological study. Am J Med. 1960 Dec;29:967–979. doi: 10.1016/0002-9343(60)90077-2. [DOI] [PubMed] [Google Scholar]
  5. LUND E. POLYVALENT, DIAGNOSTIC PNEUMOCOCCUS SERA. Acta Pathol Microbiol Scand. 1963;59:533–536. doi: 10.1111/j.1699-0463.1963.tb01256.x. [DOI] [PubMed] [Google Scholar]
  6. Page M. I., Lunn J. S. Pneumococcal serotypes associated with acute pneumonia. Am J Epidemiol. 1973 Oct;98(4):255–261. doi: 10.1093/oxfordjournals.aje.a121555. [DOI] [PubMed] [Google Scholar]
  7. Tanner E. I., Gray J. D., Rebello P. V., Gamble D. R. Terminal bronchopneumonia. A bacteriological and histological study of 111 necropsies. J Hyg (Lond) 1969 Sep;67(3):477–484. doi: 10.1017/s0022172400041899. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES