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. 1976 Aug;52(610):518–524. doi: 10.1136/pgmj.52.610.518

Acute coronary insufficiency with normal coronary arteriograms.

R M Lawson, J Rosch, S Rahimtoola
PMCID: PMC2496457  PMID: 981094

Abstract

Two patients presenting with apparent symptomatic and electrocardiographic evidence of acute coronary insufficiency and found to have normal coronary arteriograms are documented. The patients remain symptom free at follow-up 9 and 14 months later although one requires 160 mg propranolol daily. The electrocardiographic, myocardial metabolic and haemodynamic data in 413 patients with angina and normal coronary arteriograms are reviewed and the suggested aetiologies documented. Follow-up of patients in these series indicates a good prognosis for symptom-free survival.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arbogast R., Bourassa M. G. Myocardial function during atrial pacing in patients with angina pectoris and normal coronary arteriograms. Comparison with patients having significant coronary artery disease. Am J Cardiol. 1973 Sep 7;32(3):257–263. doi: 10.1016/s0002-9149(73)80130-4. [DOI] [PubMed] [Google Scholar]
  2. Bemiller C. R., Pepine C. J., Rogers A. K. Long-term observations in patients with angina and normal coronary arteriograms. Circulation. 1973 Jan;47(1):36–43. doi: 10.1161/01.cir.47.1.36. [DOI] [PubMed] [Google Scholar]
  3. Boudoulas H., Cobb T. C., Leighton R. F., Wilt S. M. Myocardial lactate production in patients with angina-like chest pain and angiographically normal coronary arteries and left ventricle. Am J Cardiol. 1974 Oct 3;34(5):501–505. doi: 10.1016/0002-9149(74)90118-0. [DOI] [PubMed] [Google Scholar]
  4. Bruschke A. V., Proudfit W. L., Sones F. M., Jr Progress study of 590 consecutive nonsurgical cases of coronary disease followed 5-9 years. I. Arterographic correlations. Circulation. 1973 Jun;47(6):1147–1153. doi: 10.1161/01.cir.47.6.1147. [DOI] [PubMed] [Google Scholar]
  5. CULLEN M. L., REESE H. L. Myocardial circulatory changes measured by clearance of Na24; effect of common duct distension on myocardial circulation. J Appl Physiol. 1952 Dec;5(6):281–284. doi: 10.1152/jappl.1952.5.6.281. [DOI] [PubMed] [Google Scholar]
  6. Dwyer E. M., Jr, Wiener L., Cox J. W. Angina pectoris in patients with normal and abnormal coronary arteriograms. Am J Cardiol. 1969 May;23(5):639–646. doi: 10.1016/0002-9149(69)90024-1. [DOI] [PubMed] [Google Scholar]
  7. Eliot R. S., Bratt G. The paradox of myocardial ischemia and necrosis in young women with normal coronary anteriograms. Relation to abnormal hemoglobin-oxygen dissociation. Am J Cardiol. 1969 May;23(5):633–638. doi: 10.1016/0002-9149(69)90023-x. [DOI] [PubMed] [Google Scholar]
  8. Forrester J. S., Herman M. V., Gorlin R. Noncoronary factors in the anginal syndrome. N Engl J Med. 1970 Oct 8;283(15):786–789. doi: 10.1056/NEJM197010082831504. [DOI] [PubMed] [Google Scholar]
  9. James T. N. Pathology of small coronary arteries. Am J Cardiol. 1967 Nov;20(5):679–691. doi: 10.1016/0002-9149(67)90012-4. [DOI] [PubMed] [Google Scholar]
  10. Kemp H. G., Elliott W. C., Gorlin R. The anginal syndrome with normal coronary arteriography. Trans Assoc Am Physicians. 1967;80:59–70. [PubMed] [Google Scholar]
  11. Kemp H. G., Elliott W. C., Gorlin R. The anginal syndrome with normal coronary arteriography. Trans Assoc Am Physicians. 1967;80:59–70. [PubMed] [Google Scholar]
  12. Kemp H. G., Jr, Vokonas P. S., Cohn P. F., Gorlin R. The anginal syndrome associated with normal coronary arteriograms. Report of a six year experience. Am J Med. 1973 Jun;54(6):735–742. doi: 10.1016/0002-9343(73)90060-0. [DOI] [PubMed] [Google Scholar]
  13. Kerin N., Macleod C. A. Coronary artery spasm associated with variant angina pectoris. Br Heart J. 1974 Feb;36(2):224–227. doi: 10.1136/hrt.36.2.224. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Likoff W., Segal B. L., Kasparian H. Paradox of normal selective coronary arteriograms in patients considered to have unmistakable coronary heart disease. N Engl J Med. 1967 May 11;276(19):1063–1066. doi: 10.1056/NEJM196705112761904. [DOI] [PubMed] [Google Scholar]
  15. Neill W. A., Huckabee W. E. Anaerobic heat production by the heart. J Clin Invest. 1966 Sep;45(9):1412–1420. doi: 10.1172/JCI105449. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Neill W. A., Judkins M. P., Dhindsa D. S., Metcalfe J., Kassebaum G., Kloster F. E. Clinically suspect ischemic heart disease not corroborated by demonstrable coronary artery disease. Physiologic investigations and clinical course. Am J Cardiol. 1972 Feb;29(2):171–179. doi: 10.1016/0002-9149(72)90626-1. [DOI] [PubMed] [Google Scholar]
  17. Neill W. A., Kassebaum D. G., Judkins M. P. Myocardial hypoxia as the basis for angina pectoris in a patient with normal coronary arteriograms. N Engl J Med. 1968 Oct 10;279(15):789–792. doi: 10.1056/NEJM196810102791502. [DOI] [PubMed] [Google Scholar]
  18. Neill W. A. Myocardial hypoxia and anerobic metabolism in coronary heart disease. Am J Cardiol. 1968 Oct;22(4):507–515. doi: 10.1016/0002-9149(68)90155-0. [DOI] [PubMed] [Google Scholar]
  19. SHEA T. M., WATSON R. M., PIOTROWSKI S. F., DERMKSIAN G., CASE R. B. Anaerobic myocardial metabolism. Am J Physiol. 1962 Sep;203:463–469. doi: 10.1152/ajplegacy.1962.203.3.463. [DOI] [PubMed] [Google Scholar]
  20. Scanlon P. J., Nemickas R., Moran J. F., Talano J. V., Amirparviz F., Pifarre R. Accelerated angina pectoris. Clinical, hemodynamic, arteriographic, and therapeutic experience in 85 patients. Circulation. 1973 Jan;47(1):19–26. doi: 10.1161/01.cir.47.1.19. [DOI] [PubMed] [Google Scholar]

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