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. 1976 Aug;52(610):535–538. doi: 10.1136/pgmj.52.610.535

Contraceptive pill-induced porphyria cutanea tarda presenting with onycholysis of the finger nails.

J P Byrne, J M Boss, R P Dawber
PMCID: PMC2496458  PMID: 981098

Abstract

A case of porphyria cutanea tarda induced by oral contraceptive pill therapy is reported, and its unusual presenting sign of onycholysis of the finger nails is noted. Reference is made to the rarity of nail changes in porphyria and the regression of the onycholysis in the patient following therapy is outlined.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Behm A. R., Unger W. P. Oral contraceptives and porphyria cutanea tarda. Can Med Assoc J. 1974 May 4;110(9):1052–1054. [PMC free article] [PubMed] [Google Scholar]
  2. Copeman P. W. Porphyria. Successful treatment by alkalinization of urine with sodium bicarbonate assessed by experimental suction blister apparatus. Br J Dermatol. 1970 Apr;82(4):385–388. doi: 10.1111/j.1365-2133.1970.tb06837.x. [DOI] [PubMed] [Google Scholar]
  3. Epstein J. H., Redeker A. G. Porphyria cutanea tarda. A study of the effect of phlebotomy. N Engl J Med. 1968 Dec 12;279(24):1301–1304. doi: 10.1056/NEJM196812122792402. [DOI] [PubMed] [Google Scholar]
  4. ORENTREICH N., HARBER L., TROMOVITCH T. A. Photosensitivity and photo-onycholysis due to demethylchlortetracycline. Arch Dermatol. 1961 May;83:730–737. doi: 10.1001/archderm.1961.01580110018003. [DOI] [PubMed] [Google Scholar]
  5. Roenigk H. H., Jr, Gottlob M. E. Estrogen-induced porphyria cutanea tarda. Report of three cases. Arch Dermatol. 1970 Sep;102(3):260–266. [PubMed] [Google Scholar]
  6. SEGAL B. M. PHOTOSENSITIVITY, NAIL DISCOLORATION, AND ONYCHOLYSIS. SIDE EFFECTS OF TETRACYCLINE THERAPY. Arch Intern Med. 1963 Aug;112:165–167. doi: 10.1001/archinte.1963.03860020063005. [DOI] [PubMed] [Google Scholar]
  7. WARIN R. P. PORPHYRIA CUTANEA TARDA ASSOCIATED WITH OESTROGEN THERAPY FOR PROSTATIC CARCINOMA. Br J Dermatol. 1963 Jul;75:298–299. [PubMed] [Google Scholar]
  8. Walsh J. R., Lobitz W. C., Jr, Mahler D. J., Kingery F. A. Phlebotomy therapy in cutaneous porphyria. Effect on iron and trace metals. Arch Dermatol. 1970 Feb;101(2):167–172. [PubMed] [Google Scholar]

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