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Annals of The Royal College of Surgeons of England logoLink to Annals of The Royal College of Surgeons of England
. 1992 Jan;74(1):13–18.

Endoprosthetic replacement for bony metastases.

D Chan 1, S R Carter 1, R J Grimer 1, R S Sneath 1
PMCID: PMC2497481  PMID: 1371043

Abstract

A series of 38 patients with long bone metastases treated at the Birmingham Bone Tumour Treatment Service with resection of the metastatic lesion and replacement of the bone defect with an endoprosthesis was reviewed. The majority of cases had pathological fractures due to a massive destructive lesion. Two-thirds of the patients had a solitary metastasis. Metastases from hypernephroma and breast carcinoma accounted for the majority of cases. All the patients were independently mobile after the endoprosthetic replacement and were pain free. The average survival rate after the endoprosthetic replacement was 14.7 months and this varies with the primary tumour. The indications for endoprosthetic replacement for the treatment of long bone metastases are outlined and the results and complications are discussed. It is concluded that endoprosthetic replacement for bony metastases is an effective palliative procedure for a selected group of patients.

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Selected References

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  1. BREMNER R. A., JELLIFFE A. M. The management of pathological fracture of the major long bones from metastatic cancer. J Bone Joint Surg Br. 1958 Nov;40-B(4):652–659. doi: 10.1302/0301-620X.40B4.652. [DOI] [PubMed] [Google Scholar]
  2. Burrows H. J., Wilson J. N., Scales J. T. Excision of tumours of humerus and femur, with restoration by internal prostheses. J Bone Joint Surg Br. 1975 May;57(2):148–159. [PubMed] [Google Scholar]
  3. Enneking W. F., Spanier S. S., Goodman M. A. A system for the surgical staging of musculoskeletal sarcoma. Clin Orthop Relat Res. 1980 Nov-Dec;(153):106–120. [PubMed] [Google Scholar]
  4. Galasko C. S. Pathological fractures secondary to metastatic cancer. J R Coll Surg Edinb. 1974 Nov;19(6):351–362. [PubMed] [Google Scholar]
  5. Habermann E. T., Lopez R. A. Metastatic disease of bone and treatment of pathological fractures. Orthop Clin North Am. 1989 Jul;20(3):469–486. [PubMed] [Google Scholar]
  6. Habermann E. T., Sachs R., Stern R. E., Hirsh D. M., Anderson W. J., Jr The pathology and treatment of metastatic disease of the femur. Clin Orthop Relat Res. 1982 Sep;(169):70–82. [PubMed] [Google Scholar]
  7. Harrington K. D. New trends in the management of lower extremity metastases. Clin Orthop Relat Res. 1982 Sep;(169):53–61. [PubMed] [Google Scholar]
  8. Harrington K. D., Sim F. H., Enis J. E., Johnston J. O., Diok H. M., Gristina A. G. Methylmethacrylate as an adjunct in internal fixation of pathological fractures. Experience with three hundred and seventy-five cases. J Bone Joint Surg Am. 1976 Dec;58(8):1047–1055. [PubMed] [Google Scholar]
  9. Keating J. F., Burke T., Macauley P. Proximal femoral replacement for pathological fracture. Injury. 1990 Jul;21(4):231–233. doi: 10.1016/0020-1383(90)90010-r. [DOI] [PubMed] [Google Scholar]
  10. Ljungberg B., Roos G., Toolanen G. Tumour DNA content and skeletal metastases in renal cell carcinoma. A preliminary report. J Bone Joint Surg Br. 1990 Jan;72(1):111–115. doi: 10.1302/0301-620X.72B1.2298767. [DOI] [PubMed] [Google Scholar]
  11. Parrish F. F., Murray J. A. Surgical treatment for secondary neoplastic fractures. A retrospective study of ninety-six patients. J Bone Joint Surg Am. 1970 Jun;52(4):665–686. [PubMed] [Google Scholar]
  12. Pongracz N., Zimmerman R., Kotz R. Orthopaedic management of bony metastases of renal cancer. Semin Surg Oncol. 1988;4(2):139–142. [PubMed] [Google Scholar]
  13. Ritschl P., Kotz R. Prosthetic implants in bone metastases of the lower limb. Ann Chir Gynaecol. 1987;76(3):159–162. [PubMed] [Google Scholar]
  14. Swanson D. A., Orovan W. L., Johnson D. E., Giacco G. Osseous metastases secondary to renal cell carcinoma. Urology. 1981 Dec;18(6):556–561. doi: 10.1016/0090-4295(81)90455-6. [DOI] [PubMed] [Google Scholar]

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