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. 1969 Feb;97(2):940–943. doi: 10.1128/jb.97.2.940-943.1969

Mutations to Spectinomycin Resistance Which Alleviate the Restriction of an Amber Suppressor by Streptomycin Resistance

Michihiko Kuwano 1, Hideya Endo 1, Yoshinari Ohnishi 1
PMCID: PMC249780  PMID: 4886300

Abstract

Unlike mutations to streptomycin resistance, which restrict the function of an SU II amber suppressor, mutations to spectinomycin resistance have no restrictive effect. Furthermore, mutations to spectinomycin resistance counteract the restrictive action of streptomycin-resistant mutations when combined in a single strain. The mutations to drug resistance, singly or in combination, do not themselves lead to any detectable suppressor activity. The effects on SU II are interpreted in terms of interactions between ribosomal elements.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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