Abstract
Arterial disease changes the shape of Doppler ultrasound waveforms recorded noninvasively from arteries in the lower limbs. These changes can be described numerically by computer analysis of waveforms, and techniques currently in use are pulsatility index, Laplace transform and principal component analysis. These waveform analysis methods allow assessment of aortoiliac disease from Doppler recordings at the femoral artery. In addition, the femorodistal segment can be evaluated by comparing femoral and distal waveforms, even in the presence of more proximal arterial disease. Other possible applications for waveform analysis include noninvasive follow-up of angioplasty or bypass grafts and the detection of early, presymptomatic arterial disease. Experience in recording Doppler waveforms is important if variability is to be minimised. Currently, these methods allow exclusion of aortoiliac disease prior to femorodistal grafting but their other potential roles require further clinical evaluation.
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Selected References
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- Baird R. N., Bird D. R., Clifford P. C., Lusby R. J., Skidmore R., Woodcock J. P. Upstream stenosis. Its diagnosis by Doppler signals from the femoral artery. Arch Surg. 1980 Nov;115(11):1316–1322. doi: 10.1001/archsurg.1980.01380110054008. [DOI] [PubMed] [Google Scholar]
- Bernstein E. F., Murphy A. E., Jr, Shea M. A., Housman L. B. Experimental and clinical experience with transcutaneous Doppler ultrasonic flowmeters. Arch Surg. 1970 Jul;101(1):21–25. doi: 10.1001/archsurg.1970.01340250023006. [DOI] [PubMed] [Google Scholar]
- Campbell W. B., Baird R. N., Cole S. E., Evans J. M., Skidmore R., Woodcock J. P. Physiological interpretation of Doppler shift waveforms: the femorodistal segment in combined disease. Ultrasound Med Biol. 1983 May-Jun;9(3):265–269. doi: 10.1016/0301-5629(83)90060-1. [DOI] [PubMed] [Google Scholar]
- Campbell W. B., Cole S. E., Skidmore R., Baird R. N. The clinician and the vascular laboratory in the diagnosis of aortoiliac stenosis. Br J Surg. 1984 Apr;71(4):302–306. doi: 10.1002/bjs.1800710418. [DOI] [PubMed] [Google Scholar]
- Campbell W. B., Skidmore R., Baird R. N. Variability and reproducibility of arterial Doppler waveforms. Ultrasound Med Biol. 1984 Sep-Oct;10(5):601–606. doi: 10.1016/0301-5629(84)90073-5. [DOI] [PubMed] [Google Scholar]
- Campbell W. B., Skidmore R., Woodcock J. P., Baird R. N. Detection of early arterial disease: a study using Doppler waveform analysis. Cardiovasc Res. 1985 Apr;19(4):206–211. doi: 10.1093/cvr/19.4.206. [DOI] [PubMed] [Google Scholar]
- Charlesworth D., Harris P. L., Cave F. D., Taylor L. Undetected aorto-iliac insufficiency: a reason for early failure of saphenous vein bypass grafts for obstruction of the superficial femoral artery. Br J Surg. 1975 Jul;62(7):567–570. doi: 10.1002/bjs.1800620716. [DOI] [PubMed] [Google Scholar]
- Demorais D., Johnston K. W. Assessment of aorto-iliac disease by non-invasive quantitative Doppler waveform analysis. Br J Surg. 1981 Nov;68(11):789–792. doi: 10.1002/bjs.1800681111. [DOI] [PubMed] [Google Scholar]
- Evans D. H., Macpherson D. S., Bentley S., Asher M. J., Bell P. R. The effect of proximal stenosis on Doppler waveforms: a comparison of three methods of waveform analysis in an animal model. Clin Phys Physiol Meas. 1981 Feb;2(1):17–25. doi: 10.1088/0143-0815/2/1/004. [DOI] [PubMed] [Google Scholar]
- Gosling R. G., Dunbar G., King D. H., Newman D. L., Side C. D., Woodcock J. P., Fitzgerald D. E., Keates J. S., MacMillan D. The quantitative analysis of occlusive peripheral arterial disease by a non-intrusive ultrasonic technique. Angiology. 1971 Jan;22(1):52–55. doi: 10.1177/000331977102200109. [DOI] [PubMed] [Google Scholar]
- Johnston K. W., Maruzzo B. C., Cobbold R. S. Doppler methods for quantitative measurement and localization of peripheral arterial occlusive disease by analysis of the blood flow velocity waveform. Ultrasound Med Biol. 1978;4(3):209–223. doi: 10.1016/0301-5629(78)90053-4. [DOI] [PubMed] [Google Scholar]
- Macpherson D. S., Evans D. H., Bell P. R. Common femoral artery Doppler wave-forms: a comparison of three methods of objective analysis with direct pressure measurements. Br J Surg. 1984 Jan;71(1):46–49. doi: 10.1002/bjs.1800710114. [DOI] [PubMed] [Google Scholar]
- Nayman J. The use of the ultrasonic flow meter in peripheral vascular disease. Aust N Z J Surg. 1974 May;44(2):157–167. doi: 10.1111/j.1445-2197.1974.tb06413.x. [DOI] [PubMed] [Google Scholar]
- Persson A. V., Gibbons G., Griffey S. Noninvasive evaluation of the aorto-iliac segment. J Cardiovasc Surg (Torino) 1981 Nov-Dec;22(6):539–542. [PubMed] [Google Scholar]
- Skidmore R., Woodcock J. P. Physiological interpretation of Doppler-shift waveforms--I. Theoretical considerations. Ultrasound Med Biol. 1980;6(1):7–10. doi: 10.1016/0301-5629(80)90057-5. [DOI] [PubMed] [Google Scholar]
- Skidmore R., Woodcock J. P. Physiological interpretation of Doppler-shift waveforms--II. Validation of the Laplace transform method for characterisation of the common femoral blood-velocity/time waveform. Ultrasound Med Biol. 1980;6(3):219–225. doi: 10.1016/0301-5629(80)90016-2. [DOI] [PubMed] [Google Scholar]
- Skidmore R., Woodcock J. P., Wells P. N. Physiological interpretation of Doppler-shift waveforms--III. Clinical results. Ultrasound Med Biol. 1980;6(3):227–231. doi: 10.1016/0301-5629(80)90017-4. [DOI] [PubMed] [Google Scholar]
- Slot H. B., Strijbosch L., Greep J. M. Interobserver variability in single-plane aortography. Surgery. 1981 Sep;90(3):497–503. [PubMed] [Google Scholar]
- Woodcock J. P., Gosling R. G., FitzGerald D. E. A new non-invasive technique for assessment of superficial femoral artery obstruction. Br J Surg. 1972 Mar;59(3):226–231. doi: 10.1002/bjs.1800590320. [DOI] [PubMed] [Google Scholar]
- Yao S. T., Hobbs J. T., Irvine W. T. Pulse examination by an ultrasonic method. Br Med J. 1968 Nov 30;4(5630):555–557. doi: 10.1136/bmj.4.5630.555. [DOI] [PMC free article] [PubMed] [Google Scholar]