Abstract
A prospective randomised trial was conducted to evaluate caudal morphine for pain relief following anal surgery. Thirty-three male patients were divided into two groups. Group I (17 patients) were given morphine 10 mg in saline 25 ml injected into the caudal epidural space at the end of surgery. Group II (16 patients) were given intramuscular morphine 10 mg on request in the postoperative period. Pain was assessed at 2, 6, 12 and 24 hours after surgery using the linear analogue of pain score. There was significant pain relief in Group I compared with Group II. There was no instance of respiratory depression in patients of either group. In Group I, five patients suffered urinary retention and three patients transient pruritus.
Full text
PDF

Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bromage P. R., Camporesi E. M., Durant P. A., Nielsen C. H. Nonrespiratory side effects of epidural morphine. Anesth Analg. 1982 Jun;61(6):490–495. [PubMed] [Google Scholar]
- Cousins M. J., Mather L. E. Intrathecal and epidural administration of opioids. Anesthesiology. 1984 Sep;61(3):276–310. [PubMed] [Google Scholar]
- Gustafsson L. L., Schildt B., Jacobsen K. Adverse effects of extradural and intrathecal opiates: report of a nationwide survey in Sweden. Br J Anaesth. 1982 May;54(5):479–486. doi: 10.1093/bja/54.5.479. [DOI] [PubMed] [Google Scholar]
- Jensen P. J., Siem-Jørgensen P., Nielsen T. B., Wichmand-Nielsen H., Wintherreich E. Epidural morphine by the caudal route for postoperative pain relief. Acta Anaesthesiol Scand. 1982 Oct;26(5):511–513. doi: 10.1111/j.1399-6576.1982.tb01809.x. [DOI] [PubMed] [Google Scholar]
- Lanz E., Theiss D., Riess W., Sommer U. Epidural morphine for postoperative analgesia: a double-blind study. Anesth Analg. 1982 Mar;61(3):236–240. [PubMed] [Google Scholar]
- Martin R., Salbaing J., Blaise G., Tétrault J. P., Tétreault L. Epidural morphine for postoperative pain relief: a dose-response curve. Anesthesiology. 1982 Jun;56(6):423–426. doi: 10.1097/00000542-198206000-00002. [DOI] [PubMed] [Google Scholar]
