Abstract
Eighteen patients with local recurrence of colorectal cancer have been treated by external beam radiotherapy for pain relief. Seven received a fractionated course of 4500cGy and the remainder received single fractions of 1000cGy, a number being treated more than once. The median survival for all patients once recurrence had produced pain was 7 months. Treatment benefit was recorded in 71% treated by fractionated courses and in 66% by single fractions. The duration of pain relief was 3 months for each method. The repeatability of single fraction treatment indicates that this is a worthwhile alternative technique, particularly for those in poor general condition.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Arnott S. J. Colorectal cancer. Radiotherapy. Recent Results Cancer Res. 1982;83:113–125. [PubMed] [Google Scholar]
- Gunderson L. L., Sosin H. Areas of failure found at reoperation (second or symptomatic look) following "curative surgery" for adenocarcinoma of the rectum. Clinicopathologic correlation and implications for adjuvant therapy. Cancer. 1974 Oct;34(4):1278–1292. doi: 10.1002/1097-0142(197410)34:4<1278::aid-cncr2820340440>3.0.co;2-f. [DOI] [PubMed] [Google Scholar]
- Mendenhall W. M., Million R. R., Pfaff W. W. Patterns of recurrence in adenocarcinoma of the rectum and rectosigmoid treated with surgery alone: implications in treatment planning with adjuvant radiation therapy. Int J Radiat Oncol Biol Phys. 1983 Jul;9(7):977–985. doi: 10.1016/0360-3016(83)90384-x. [DOI] [PubMed] [Google Scholar]
- Morson B. C., Bussey H. J. Surgical pathology of rectal cancer in relation to adjuvant radiotherapy. Br J Radiol. 1967 Mar;40(471):161–165. doi: 10.1259/0007-1285-40-471-161. [DOI] [PubMed] [Google Scholar]
- Stearns M. W., Jr, Leaming R. H. Irradiation in inoperable cancer. JAMA. 1975 Mar 31;231(13):1388–1388. [PubMed] [Google Scholar]
- WANG C. C., SCHULZ M. D. The role of radiation therapy in the management of carcinoma of the sigmoid, rectosigmoid, and rectum. Radiology. 1962 Jul;79:1–5. doi: 10.1148/79.1.1. [DOI] [PubMed] [Google Scholar]
- WILLIAMS I. G., SHULMAN I. M., TODD I. P. The treatment of recurrent carcinoma of the rectum by supervoltage x-ray therapy. Br J Surg. 1957 Mar;44(187):506–508. doi: 10.1002/bjs.18004418715. [DOI] [PubMed] [Google Scholar]