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Annals of The Royal College of Surgeons of England logoLink to Annals of The Royal College of Surgeons of England
. 1988 Jul;70(4):246–248.

Wide excision of primary breast cancer: the incidence of residual carcinoma at the site of excision.

H C Umpleby 1, A Herbert 1, G T Royle 1, I Taylor 1
PMCID: PMC2498777  PMID: 2843075

Abstract

Fifty-one consecutive women with early breast cancer underwent wide excision and axillary clearance. After wide excision five biopsies were taken from the walls of the cavity. On histological examination tumour was present in the cavity biopsies in 13 cases (25%). The presence of ductal carcinoma in situ in the primary tumour was not associated with an increased number of positive cavity biopsies. In nine cases incomplete excision was due to separate foci of invasive or in situ carcinoma, in two cases tumour was contiguous with the primary carcinoma and in two, separate foci and contiguous disease both occurred. The high incidence of residual local tumour after wide excision of breast cancer demands the need for postoperative irradiation to the breast and frequent review.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cahill C. J., Gibbs N. M., Boulter P. S., Brient M. J., Price J. L. Invasive breast cancer--the tip of an iceberg. Ann R Coll Surg Engl. 1983 Nov;65(6):356–359. [PMC free article] [PubMed] [Google Scholar]
  2. Chetty U., Forrest A. P. Breast conservation. Br J Surg. 1986 Aug;73(8):599–600. doi: 10.1002/bjs.1800730802. [DOI] [PubMed] [Google Scholar]
  3. Fentiman I. S., Fagg N., Millis R. R., Hayward J. L. In situ ductal carcinoma of the breast: implications of disease pattern and treatment. Eur J Surg Oncol. 1986 Sep;12(3):261–266. [PubMed] [Google Scholar]
  4. Fisher B., Bauer M., Margolese R., Poisson R., Pilch Y., Redmond C., Fisher E., Wolmark N., Deutsch M., Montague E. Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N Engl J Med. 1985 Mar 14;312(11):665–673. doi: 10.1056/NEJM198503143121101. [DOI] [PubMed] [Google Scholar]
  5. Fisher E. R., Sass R., Fisher B., Gregorio R., Brown R., Wickerham L. Pathologic findings from the National Surgical Adjuvant Breast Project (protocol 6). II. Relation of local breast recurrence to multicentricity. Cancer. 1986 May 1;57(9):1717–1724. doi: 10.1002/1097-0142(19860501)57:9<1717::aid-cncr2820570902>3.0.co;2-h. [DOI] [PubMed] [Google Scholar]
  6. Lagios M. D., Richards V. E., Rose M. R., Yee E. Segmental mastectomy without radiotherapy. Short-term follow-up. Cancer. 1983 Dec 1;52(11):2173–2179. doi: 10.1002/1097-0142(19831201)52:11<2173::aid-cncr2820521133>3.0.co;2-0. [DOI] [PubMed] [Google Scholar]
  7. Lesser M. L., Rosen P. P., Kinne D. W. Multicentricity and bilaterality in invasive breast carcinoma. Surgery. 1982 Feb;91(2):234–240. [PubMed] [Google Scholar]
  8. Skjørten F., Amlie E., Larsen K. A. On the occurrence of focal, occult in situ and invasive carcinoma in 250 mastectomy specimens. Eur J Surg Oncol. 1986 Jun;12(2):117–121. [PubMed] [Google Scholar]
  9. Veronesi U., Saccozzi R., Del Vecchio M., Banfi A., Clemente C., De Lena M., Gallus G., Greco M., Luini A., Marubini E. Comparing radical mastectomy with quadrantectomy, axillary dissection, and radiotherapy in patients with small cancers of the breast. N Engl J Med. 1981 Jul 2;305(1):6–11. doi: 10.1056/NEJM198107023050102. [DOI] [PubMed] [Google Scholar]
  10. Westman-Naeser S., Bengtsson E., Eriksson O., Jarkrans T., Nordin B., Stenkvist B. Multifocal breast carcinoma. Am J Surg. 1981 Aug;142(2):255–257. doi: 10.1016/0002-9610(81)90288-9. [DOI] [PubMed] [Google Scholar]

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