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. 1989 Jan;71(1):54–56.

Viable intraluminal tumour cells and local/regional tumour growth in experimental colon cancer.

P J O'Dwyer 1, E W Martin Jr 1
PMCID: PMC2498877  PMID: 2923422

Abstract

To determine if viable intraluminal tumour cells can leak through a watertight anastomosis and cause local/regional (extraluminal) tumour growth, tumour cells were introduced 2 cm proximal to a colonic anastomosis following laparotomy in a Wistar/Furth rat colon cancer model. Local/regional tumour growth was observed in all rats except a sham anastomotic group. No intraluminal tumour growth was observed in either group. Viable intraluminal tumour cells cause local/regional tumour growth by leakage through a clinically intact anastomosis and may be an important cause of local/regional tumour growth in human colorectal cancer.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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