Skip to main content
Annals of The Royal College of Surgeons of England logoLink to Annals of The Royal College of Surgeons of England
. 1990 Jul;72(4):266–269.

Pancreaticogastrostomy after pancreaticoduodenectomy.

J W Bradbeer 1, C D Johnson 1
PMCID: PMC2499216  PMID: 2166459

Abstract

Although the mortality following pancreaticoduodenectomy has fallen and is now below 5%, overall 14% of patients develop a leak at the pancreatic anastomosis. This complication carries a 24% mortality rate when pancreaticojejunostomy is the method of reconstruction. In order to reduce the incidence of this complication, pancreaticogastrostomy can be performed following pancreaticoduodenectomy. A total of 41 patients underwent this operation between 1968 and 1989. The indications for operations were carcinoma of the head of the pancreas (n = 19), carcinoma of the ampulla (n = 12), carcinoma of the lower end of the common bile duct (n = 6), chronic pancreatitis (n = 3) and one patient with a nonfunctioning islet cell tumour. One patient developed a pancreatic fistula which closed spontaneously in 5 days. This patient is alive and well 36 months after operation. Pancreaticogastrostomy with pancreatic duct to gastric mucosa anastomosis is recommended as a safe and straight-forward method of reconstruction following pancreaticoduodenectomy.

Full text

PDF
266

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brooks J. R., Culebras J. M. Cancer of the pancreas. Palliative operation, Whipple procedure, or total pancreatectomy? Am J Surg. 1976 Apr;131(4):516–520. doi: 10.1016/0002-9610(76)90167-7. [DOI] [PubMed] [Google Scholar]
  2. DILL-RUSSELL A. S. Pancreaticogastrostomy. Lancet. 1952 Mar 22;1(6708):589–590. doi: 10.1016/s0140-6736(52)90101-3. [DOI] [PubMed] [Google Scholar]
  3. Flautner L., Tihanyi T., Szécsény A. Pancreatogastrostomy: an ideal complement to pancreatic head resection with preservation of the pylorus in the treatment of chronic pancreatitis. Am J Surg. 1985 Nov;150(5):608–611. doi: 10.1016/0002-9610(85)90446-5. [DOI] [PubMed] [Google Scholar]
  4. Grace P. A., Pitt H. A., Tompkins R. K., DenBesten L., Longmire W. P., Jr Decreased morbidity and mortality after pancreatoduodenectomy. Am J Surg. 1986 Jan;151(1):141–149. doi: 10.1016/0002-9610(86)90024-3. [DOI] [PubMed] [Google Scholar]
  5. Herter F. P., Cooperman A. M., Ahlborn T. N., Antinori C. Surgical experience with pancreatic and periampullary cancer. Ann Surg. 1982 Mar;195(3):274–281. doi: 10.1097/00000658-198203000-00006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. INGEBRIGTSEN R., LANGFELDT E. Pancreaticogastrostomy. Lancet. 1952 Aug 9;2(6728):270–271. doi: 10.1016/s0140-6736(52)92384-2. [DOI] [PubMed] [Google Scholar]
  7. Icard P., Dubois F. Pancreaticogastrostomy following pancreatoduodenectomy. Ann Surg. 1988 Mar;207(3):253–256. doi: 10.1097/00000658-198803000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Ihse I., Lilja P., Arnesjö B., Bengmark S. Total pancreatectomy for cancer. An appraisal of 65 cases. Ann Surg. 1977 Dec;186(6):675–680. doi: 10.1097/00000658-197712000-00002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Jones B. A., Langer B., Taylor B. R., Girotti M. Periampullary tumors: which ones should be resected? Am J Surg. 1985 Jan;149(1):46–52. doi: 10.1016/s0002-9610(85)80008-8. [DOI] [PubMed] [Google Scholar]
  10. Kapur B. M. Pancreaticogastrostomy in pancreaticoduodenal resection for ampullary carcinoma: experience in thirty-one cases. Surgery. 1986 Sep;100(3):489–493. [PubMed] [Google Scholar]
  11. Lerut J. P., Gianello P. R., Otte J. B., Kestens P. J. Pancreaticoduodenal resection. Surgical experience and evaluation of risk factors in 103 patients. Ann Surg. 1984 Apr;199(4):432–437. doi: 10.1097/00000658-198404000-00010. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Lygidakis N. J., van der Hyde M. N., Houthoff H. J., Schipper M. E., Huibregtse K., Tytgat G. N., Lubber M. J., Reeders J. W., Bosey M. M., Oosting J. Resectional surgical procedures for carcinoma of the head of the pancreas. Surg Gynecol Obstet. 1989 Feb;168(2):157–165. [PubMed] [Google Scholar]
  13. MILLBOURN E. Pancreatico-gastrostomy in pancreatico-duodenal resection for carcinoma of the head of the pancreas or the papilla of Vater. Acta Chir Scand. 1958 Dec 8;116(1):12–27. [PubMed] [Google Scholar]
  14. Mackie J. A., Rhoads J. E., Park C. D. Pancreaticogastrostomy: a further evaluation. Ann Surg. 1975 May;181(5):541–545. doi: 10.1097/00000658-197505000-00006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. NANSON E. M. An unusual case of carcinoma of the head of the pancreas. Br J Surg. 1954 Jan;41(168):439–441. doi: 10.1002/bjs.18004116830. [DOI] [PubMed] [Google Scholar]
  16. Neoptolemos J. P., Talbot I. C., Carr-Locke D. L., Shaw D. E., Cockleburgh R., Hall A. W., Fossard D. P. Treatment and outcome in 52 consecutive cases of ampullary carcinoma. Br J Surg. 1987 Oct;74(10):957–961. doi: 10.1002/bjs.1800741025. [DOI] [PubMed] [Google Scholar]
  17. Obertop H., Bruining H. A., Schattenkerk M. E., Eggink W. F., Jeekel J., Van Houten H. Operative approach to cancer of the head of the pancreas and the peri-ampullary region. Br J Surg. 1982 Oct;69(10):573–576. doi: 10.1002/bjs.1800691005. [DOI] [PubMed] [Google Scholar]
  18. Piorkowski R. J., Blievernicht S. W., Lawrence W., Jr, Madariaga J., Horsley J. S., 3rd, Neifeld J. P., Terz J. J. Pancreatic and periampullary carcinoma. Experience with 200 patients over a 12 year period. Am J Surg. 1982 Feb;143(2):189–193. doi: 10.1016/0002-9610(82)90064-2. [DOI] [PubMed] [Google Scholar]
  19. Pliam M. B., ReMine W. H. Further evaluation of total pancreatectomy. Arch Surg. 1975 May;110(5):506–512. doi: 10.1001/archsurg.1975.01360110052010. [DOI] [PubMed] [Google Scholar]
  20. Prevost F., Roos S., Rousset J. F., Fourtanier G., Escat J. Traitement chirurgical des adénocarcinomes de la tête du pancréas et de la région péri-ampullaire. A propos de 213 cas. Ann Chir. 1987 Feb;41(1):12–17. [PubMed] [Google Scholar]
  21. SILVERSTONE M. Pancreaticoduodenectomy and pancreaticogastrostomy; a five-year survival, with notes on the metabolism. Br J Surg. 1956 Nov;44(185):299–302. doi: 10.1002/bjs.18004418513. [DOI] [PubMed] [Google Scholar]
  22. Scott H. W., Jr, Dean R. H., Parker T., Avant G. The role of vagotomy in pancreaticoduodenectomy. Ann Surg. 1980 Jun;191(6):688–696. doi: 10.1097/00000658-198006000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Tarazi R. Y., Hermann R. E., Vogt D. P., Hoerr S. O., Esselstyn C. B., Jr, Cooperman A. M., Steiger E., Grundfest S. Results of surgical treatment of periampullary tumors: a thirty-five-year experience. Surgery. 1986 Oct;100(4):716–723. [PubMed] [Google Scholar]
  24. Tashiro S., Murata E., Hiraoka T., Nakakuma K., Watanabe E., Miyauchi Y. New technique for pancreaticojejunostomy using a biological adhesive. Br J Surg. 1987 May;74(5):392–394. doi: 10.1002/bjs.1800740523. [DOI] [PubMed] [Google Scholar]
  25. Telford G. L., Mason G. R. Pancreaticogastrostomy: clinical experience with a direct pancreatic-duct-to-gastric-mucosa anastomosis. Am J Surg. 1984 Jun;147(6):832–837. doi: 10.1016/0002-9610(84)90214-9. [DOI] [PubMed] [Google Scholar]
  26. Trede M., Schwall G. The complications of pancreatectomy. Ann Surg. 1988 Jan;207(1):39–47. doi: 10.1097/00000658-198801000-00009. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Trede M. Treatment of pancreatic carcinoma: the surgeon's dilemma. Br J Surg. 1987 Feb;74(2):79–80. doi: 10.1002/bjs.1800740202. [DOI] [PubMed] [Google Scholar]
  28. WELLS C., SHEPHERD J. A., GIBBON N. Pancreaticogastrostomy. Lancet. 1952 Mar 22;1(6708):588–589. doi: 10.1016/s0140-6736(52)90100-1. [DOI] [PubMed] [Google Scholar]
  29. Warren K. W., Christophi C., Armendariz R., Basu S. Current trends in the diagnosis and treatment of carcinoma of the pancreas. Am J Surg. 1983 Jun;145(6):813–818. doi: 10.1016/0002-9610(83)90149-6. [DOI] [PubMed] [Google Scholar]
  30. van Heerden J. A., McIlrath D. C., Dozois R. R., Adson M. A. Radical pancreatoduodenectomy--a procedure to be abandoned? Mayo Clin Proc. 1981 Oct;56(10):601–606. [PubMed] [Google Scholar]
  31. van Heerden J. A. Pancreatic resection for carcinoma of the pancreas: Whipple versus total pancreatectomy--an institutional perspective. World J Surg. 1984 Dec;8(6):880–888. doi: 10.1007/BF01656028. [DOI] [PubMed] [Google Scholar]

Articles from Annals of The Royal College of Surgeons of England are provided here courtesy of The Royal College of Surgeons of England

RESOURCES