Skip to main content
NCBI home page
Annals of The Royal College of Surgeons of England logoLink to Annals of The Royal College of Surgeons of England
. 1990 Jul;72(4):221–224.

LHRH analogue for treatment of recurrent and refractory mastalgia.

H Hamed 1, M Caleffi 1, M A Chaudary 1, I S Fentiman 1
PMCID: PMC2499253  PMID: 2143364

Abstract

The LHRH analogue Zoladex was used to treat 21 premenopausal women with severe recurrent or refractory breast pain. Severity and pattern of mastalgia, whether cyclical or non-cyclical, was assessed using self-administered record cards. Symptom relief was achieved in 17 (81%) of the patients. This study showed Zoladex to be an effective short-term treatment for refractory and recurrent mastalgia.

Full text

PDF
221

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ernster V. L., Goodson W. H., 3rd, Hunt T. K., Petrakis N. L., Sickles E. A., Miike R. Vitamin E and benign breast "disease": a double-blind, randomized clinical trial. Surgery. 1985 Apr;97(4):490–494. [PubMed] [Google Scholar]
  2. Fentiman I. S., Caleffi M., Brame K., Chaudary M. A., Hayward J. L. Double-blind controlled trial of tamoxifen therapy for mastalgia. Lancet. 1986 Feb 8;1(8476):287–288. doi: 10.1016/s0140-6736(86)90825-1. [DOI] [PubMed] [Google Scholar]
  3. Fentiman I. S., Caleffi M., Hamed H., Chaudary M. A. Dosage and duration of tamoxifen treatment for mastalgia: a controlled trial. Br J Surg. 1988 Sep;75(9):845–846. doi: 10.1002/bjs.1800750905. [DOI] [PubMed] [Google Scholar]
  4. Fentiman I. S. Tamoxifen and mastalgia. An emerging indication. Drugs. 1986 Dec;32(6):477–480. doi: 10.2165/00003495-198632060-00001. [DOI] [PubMed] [Google Scholar]
  5. Fraser H. M., Sandow J. Suppression of follicular maturation by infusion of a luteinizing hormone-releasing hormone agonist starting during the late luteal phase in the stumptailed macaque monkey. J Clin Endocrinol Metab. 1985 Mar;60(3):579–584. doi: 10.1210/jcem-60-3-579. [DOI] [PubMed] [Google Scholar]
  6. Kumar S., Mansel R. E., Hughes L. E., Woodhead J. S., Edwards C. A., Scanlon M. F., Newcombe R. G. Prolactin response to thyrotropin-releasing hormone stimulation and dopaminergic inhibition in benign breast disease. Cancer. 1984 Mar 15;53(6):1311–1315. doi: 10.1002/1097-0142(19840315)53:6<1311::aid-cncr2820530615>3.0.co;2-r. [DOI] [PubMed] [Google Scholar]
  7. Preece P. E., Baum M., Mansel R. E., Webster D. J., Fortt R. W., Gravelle I. H., Hughes L. E. Importance of mastalgia in operable breast cancer. Br Med J (Clin Res Ed) 1982 May 1;284(6325):1299–1300. doi: 10.1136/bmj.284.6325.1299. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Pye J. K., Mansel R. E., Hughes L. E. Clinical experience of drug treatments for mastalgia. Lancet. 1985 Aug 17;2(8451):373–377. doi: 10.1016/s0140-6736(85)92506-1. [DOI] [PubMed] [Google Scholar]
  9. Sitruk-ware L. R., Sterkers N., Mowszowicz I., Mauvais-Jarvis P. Inadequate corpus luteal function in women with benign breast diseases. J Clin Endocrinol Metab. 1977 Apr;44(4):771–774. doi: 10.1210/jcem-44-4-771. [DOI] [PubMed] [Google Scholar]
  10. Wang D. Y., Fentiman I. S. Epidemiology and endocrinology of benign breast disease. Breast Cancer Res Treat. 1985;6(1):5–36. doi: 10.1007/BF01806008. [DOI] [PubMed] [Google Scholar]
  11. Wisbey J. R., Kumar S., Mansel R. E., Peece P. E., Pye J. K., Hughes L. E. Natural history of breast pain. Lancet. 1983 Sep 17;2(8351):672–674. doi: 10.1016/s0140-6736(83)92543-6. [DOI] [PubMed] [Google Scholar]

Articles from Annals of The Royal College of Surgeons of England are provided here courtesy of The Royal College of Surgeons of England

RESOURCES