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. 1969 Aug;99(2):469–471. doi: 10.1128/jb.99.2.469-471.1969

Isolation of an Antigen of Neisseria gonorrhoeae Involved in the Human Immune Response to Gonococcal Infection

John D Schmale a, Dan G Danielsson a,1, Joseph F Smith a, Linda Lee a, William L Peacock Jr a
PMCID: PMC250040  PMID: 4980063

Abstract

Ion-exchange chromatography was used to isolate a fraction from disrupted gonococci which reacts with sera from patients with gonococcal disease in complement-fixation and gel-diffusion tests. This antigenic fraction was shown to be the same as that previously described as having been isolated by gel filtration. The method reported here has the advantage of greater rapidity of isolation together with some improvement in purity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Danielsson D. G., Schmale J. D., Peacock W. L., Jr, Thayer J. D. Antigens of Neisseria gonorrhoeae: characterization by gel filtration, complement fixation, and agar-gel diffusion of antigens of gonococcal protoplasm. J Bacteriol. 1969 Mar;97(3):1012–1017. doi: 10.1128/jb.97.3.1012-1017.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
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