Abstract
It was found that cyanide can partially reverse as well as arrest the transformation of a newly transformed deoxyribonuclease-treated culture for 6 to 8 min after the addition of the enzyme. These findings strongly suggest that deoxyribonucleic acid which attained deoxyribonuclease-insensitivity is not necessarily in the cell, but stored in some region peripheral to the membrane, and that a rate-limiting, energy-dependent step is required to transport this deoxyribonucleic acid into the cell.
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Selected References
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