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. 2008 Aug;10(8):817–827. doi: 10.1593/neo.08402

Figure 5.

Figure 5

Induction of HIF-1α in local and metastatic NB variants by the hypoxia mimetic DFX. (A) SY5Y.Ad and SY5Y.Lu2 variant cells and (B) MHH.Ad and MHH.Lu3 variant cells were treated with 0, 25, and 50 µM DFX for 24 hours. HIF-1α and ERK2 (loading control) expression was detected by Western blot analysis. Presented are the results of one representative blot and its densitometry analysis of four independent experiments.