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. 1988 Feb;62(2):655–658. doi: 10.1128/jvi.62.2.655-658.1988

The art gene product of human immunodeficiency virus is required for replication.

E Terwilliger 1, R Burghoff 1, R Sia 1, J Sodroski 1, W Haseltine 1, C Rosen 1
PMCID: PMC250587  PMID: 3257271

Abstract

A mutation that alters the initiation codon of the art gene of the human immunodeficiency virus renders the virus replication defective. The replication defect of this mutation can be complemented in trans by the art gene product. These findings indicate that the art protein is essential for replication and, as such, represents a good target for development of new antiviral agents that could be useful in the control of human immunodeficiency virus infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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