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. 1972 Oct;112(1):413–420. doi: 10.1128/jb.112.1.413-420.1972

Consequences of Glycerol Deprivation on the Synthesis of Membrane Components in a Glycerol Auxotroph of Staphylococcus aureus

Paul H Ray a, Thomas T Lillich a, David C White a,1
PMCID: PMC251426  PMID: 5079070

Abstract

In a glycerol auxotroph of Staphylococcus aureus, the deprivation of glycerol affected the formation of certain membrane components. (i) There was synthesis of fatty acids at the predeprivation rate even though the fatty acids synthesized accumulated as free fatty acids rather than as esterified fatty acids; (ii) there was a complete cessation of phospholipid and vitamin K isoprenologue biosynthesis; (iii) there was conservation of the glycerol esters of the complex phospholipids and glucolipids; (iv) there was an immediate decrease in the rate of synthesis of monoglucoslydiglyceride (30%) and diglucosyldiglyceride (60%); (v) there was a 50% decrease in the rate of synthesis of the polar and nonpolar carotenoids; (vi) there was synthesis of protoheme, heme a, and nonspecific membrane protein at the predeprivation rate; and (vii) there was an abrupt cessation in the formation of new, functional glycine transport activity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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