Abstract
The total lipid content of Mycoplasma neurolyticum comprises about 14% of the dry weight of the organisms and is about equally distributed between the phospholipid and the neutral-glycolipid fractions. The neutral lipids were identified as triglycerides, diglycerides, and cholesterol. The glycolipid fraction contained 1-O-β-glucopyranosyl-d-2,3-diglyceride and 1-[O-β-d-glycopyranosyl-(1→6)-O-β-d-glucopyranosyl]-d-2,3-diglyceride. The latter lipid is structurally identical to the diglucosyl diglyceride which occurs in Staphylococcus aureus. The phospholipids of the organism consist of a fully acylated glycerophosphoryl-glycerophosphoryl glycerol, phosphatidic acid, diphosphatidyl glycerol, phosphatidyl glycerol, and amino acyl esters of phosphatidyl glycerol. Phosphatidic acid and phosphatidyl glycerol account for greater than 90% of the phospholipids of organisms in the exponential phase of growth. The predominant fatty acids found in all of the acyl lipids were palmitic, stearic, and oleic acids.
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- Plackett P., Marmion B. P., Shaw E. J., Lemcke R. M. Immunochemical analysis of Mycoplasma pneumoniae. 3. Separation and chemical identification of serologically active lipids. Aust J Exp Biol Med Sci. 1969 Apr;47(2):171–195. doi: 10.1038/icb.1969.19. [DOI] [PubMed] [Google Scholar]
- Plackett P., Smith P. F., Mayberry W. R. Lipids of a sterol-nonrequiring Mycoplasma. J Bacteriol. 1970 Nov;104(2):798–807. doi: 10.1128/jb.104.2.798-807.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Smith P. F., Koostra W. L. Phospholipids and glycolipids of sterol-requiring Mycoplasma. J Bacteriol. 1967 Jun;93(6):1853–1862. doi: 10.1128/jb.93.6.1853-1862.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- TULLY J. G. PRODUCTION AND BIOLOGICAL CHARACTERISTICS OF AN EXTRACELLULAR NEUROTOXIN FROM MYCOPLASMA NEUROLYTICUM. J Bacteriol. 1964 Aug;88:381–388. doi: 10.1128/jb.88.2.381-388.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WELLS M. A., DITTMER J. C. THE USE OF SEPHADEX FOR THE REMOVAL OF NONLIPID CONTAMINANTS FROM LIPID EXTRACTS. Biochemistry. 1963 Nov-Dec;2:1259–1263. doi: 10.1021/bi00906a015. [DOI] [PubMed] [Google Scholar]
- Wright D. N. Nature of penicillin-induced growth inhibition of Mycoplasma neurolyticum. J Bacteriol. 1967 Jan;93(1):185–190. doi: 10.1128/jb.93.1.185-190.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]