Fig. 21.

Marine terpenoids. A. Incorporation studies of caulerpenyne have clearly shown this metabolite to arise from the MEP pathway [233]. A diverse set of acylated metabolites has been identified. B. The order of lipase reactions leading to the highly toxic secretion oxytoxin-2 are believed to follow the upper path in vivo [236]. Other cyclized species, such as 17F–H, are known in this metabolic family.