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. 1973 Jan;113(1):504–507. doi: 10.1128/jb.113.1.504-507.1973

Reversal by Aromatic Amino Acids of 2-Thiazole-dl-Alanine Inhibition of Salmonella typhimurium

M B Bahramian a,1, R B Middleton a,2
PMCID: PMC251655  PMID: 4569697

Abstract

Of 21 l-amino acids tested (at 1.2 × 10−4m), only histidine and the aromatic amino acids (phenylalanine, tryptophan, and tyrosine) protect Salmonella typhimurium strains from inhibition of growth and immediately reverse the growth inhibition by 5 × 10−4m 2-thiazole-dl-alanine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AMES B. N., GARRY B., HERZENBERG L. A. The genetic control of the enzymes of histidine biosynthesis in Salmonella typhimurium. J Gen Microbiol. 1960 Apr;22:369–378. doi: 10.1099/00221287-22-2-369. [DOI] [PubMed] [Google Scholar]
  2. AMES B. N., MARTIN R. G., GARRY B. J. The first step of histidine biosynthesis. J Biol Chem. 1961 Jul;236:2019–2026. [PubMed] [Google Scholar]
  3. AMES G. F. UPTAKE OF AMINO ACIDS BY SALMONELLA TYPHIMURIUM. Arch Biochem Biophys. 1964 Jan;104:1–18. doi: 10.1016/s0003-9861(64)80028-x. [DOI] [PubMed] [Google Scholar]
  4. Ames G. F., Lever J. Components of histidine transport: histidine-binding proteins and hisP protein. Proc Natl Acad Sci U S A. 1970 Aug;66(4):1096–1103. doi: 10.1073/pnas.66.4.1096. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Ames G. F., Roth J. R. Histidine and aromatic permeases of Salmonella typhimurim. J Bacteriol. 1968 Nov;96(5):1742–1749. doi: 10.1128/jb.96.5.1742-1749.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Brown K. D. Maintenance and exchange of the aromatic amino acid pool in Escherichia coli. J Bacteriol. 1971 Apr;106(1):70–81. doi: 10.1128/jb.106.1.70-81.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Demerec M. "SELFERS"-ATTRIBUTED TO UNEQUAL CROSSOVERS IN SALMONELLA. Proc Natl Acad Sci U S A. 1962 Oct;48(10):1696–1704. doi: 10.1073/pnas.48.10.1696. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. MOYED H. S., FRIEDMAN M. Interference with feedback control; a mechanism of antimetabolite action. Science. 1959 Apr 10;129(3354):968–969. doi: 10.1126/science.129.3354.968. [DOI] [PubMed] [Google Scholar]
  9. MOYED H. S. Interference with the feed-back control of histidine biosynthesis. J Biol Chem. 1961 Aug;236:2261–2267. [PubMed] [Google Scholar]
  10. Shifrin S., Ames B. N., FerroLuzzi-Ames G. Effect of the alpha-hydrazino analogue of histidine on histidine transport and arginine biosynthesis. J Biol Chem. 1966 Jul 25;241(14):3424–3429. [PubMed] [Google Scholar]

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