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. Author manuscript; available in PMC: 2008 Aug 18.
Published in final edited form as: Biochemistry. 2006 Jun 27;45(25):7844–7853. doi: 10.1021/bi0526074

Figure 7.

Figure 7

DSC of apo- and holo-TRAP. Scanning thermograms of apo (solid line) and holo-TRAP (dashed line) reveal (1) the hyperthermal stability of the oligomeric protein, (2) the thermal separation between tryptophan dissociation and global unfolding of the protein, and (3) the linearity of the partial specific heat capacity in the temperature range studied by ITC (25-50 °C). Quantitative deconvolution analyses of these traces is not possible however, due to the absence of a post-transition baseline and by lack of reversibility of the high temperature global unfolding (as illustrated by the re-scan of holo-TRAP, dotted line).