Abstract
Brain materials from four cases of subacute sclerosing panencephalitis were examined by immune fluorescence with monoclonal antibodies against five structural components of measles virus. All five antigens including the matrix component were present in the brain tissues of all cases. A defective Vero cell-associated virus isolate from one of the cases produced all of the structural components except the matrix protein.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Baczko K., Carter M. J., Billeter M., ter Meulen V. Measles virus gene expression in subacute sclerosing panencephalitis. Virus Res. 1984 Oct;1(7):585–595. doi: 10.1016/0168-1702(84)90015-7. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Budka H., Lassmann H., Popow-Kraupp T. Measles virus antigen in panencephalitis. An immunomorphological study stressing dendritic involvement in SSPE. Acta Neuropathol. 1982;56(1):52–62. doi: 10.1007/BF00691182. [DOI] [PubMed] [Google Scholar]
- Hall W. W., Choppin P. W. Evidence for lack of synthesis of the M polypeptide of measles virus in brain cells in subacute sclerosing panencephalitis. Virology. 1979 Dec;99(2):443–447. doi: 10.1016/0042-6822(79)90026-6. [DOI] [PubMed] [Google Scholar]
- Hall W. W., Choppin P. W. Measles-virus proteins in the brain tissue of patients with subacute sclerosing panencephalitis: absence of the M protein. N Engl J Med. 1981 May 7;304(19):1152–1155. doi: 10.1056/NEJM198105073041906. [DOI] [PubMed] [Google Scholar]
- Hall W. W., Lamb R. A., Choppin P. W. Measles and subacute sclerosing panencephalitis virus proteins: lack of antibodies to the M protein in patients with subacute sclerosing panencephalitis. Proc Natl Acad Sci U S A. 1979 Apr;76(4):2047–2051. doi: 10.1073/pnas.76.4.2047. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Johnson K. P., Norrby E., Swoveland P., Carrigan D. R. Experimental subacute sclerosing panencephalitis: selective disappearance of measles virus matrix protein from the Central nervous system. J Infect Dis. 1981 Aug;144(2):161–169. doi: 10.1093/infdis/144.2.161. [DOI] [PubMed] [Google Scholar]
- Kapsenberg J. G., de Ronde-Verloop F. M. Subacute scleroserende panencephalitis; isolatie van mazelenvirus. Ned Tijdschr Geneeskd. 1973 Dec 15;117(50):1880–1884. [PubMed] [Google Scholar]
- Norrby E. A carrier cell line of measles virus in Lu 106 cells. Arch Gesamte Virusforsch. 1967;20(2):215–224. doi: 10.1007/BF01241275. [DOI] [PubMed] [Google Scholar]
- Norrby E., Chen S. N., Togashi T., Shesberadaran H., Johnson K. P. Five measles virus antigens demonstrated by use of mouse hybridoma antibodies in productively infected tissue culture cells. Arch Virol. 1982;71(1):1–11. doi: 10.1007/BF01315171. [DOI] [PubMed] [Google Scholar]
- Norrby E., Enders-Ruckle G., Meulen V. Differences in the appearance of antibodies to structural components of measles virus after immunization with inactivated and live virus. J Infect Dis. 1975 Sep;132(3):262–269. doi: 10.1093/infdis/132.3.262. [DOI] [PubMed] [Google Scholar]
- Sheshberadaran H., Chen S. N., Norrby E. Monoclonal antibodies against five structural components of measles virus. I. Characterization of antigenic determinants on nine strains of measles virus. Virology. 1983 Jul 30;128(2):341–353. doi: 10.1016/0042-6822(83)90261-1. [DOI] [PubMed] [Google Scholar]
- Wechsler S. L., Meissner H. C. Measles and SSPE viruses: similarities and differences. Prog Med Virol. 1982;28:65–95. [PubMed] [Google Scholar]
- ter Meulen V., Carter M. J. Measles virus persistency and disease. Prog Med Virol. 1984;30:44–61. [PubMed] [Google Scholar]