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. 1968 Dec;96(6):2049–2053. doi: 10.1128/jb.96.6.2049-2053.1968

Stability of the Nucleic Acids of L Cells After Infection with the Meningopneumonitis Agent

Hsiu-San Lin a,1
PMCID: PMC252557  PMID: 5724971

Abstract

The stability of host nucleic acids in L cells infected with Chlamydia psittaci (strain meningopneumonitis) was studied. The L cells were prelabeled with either 32P-orthophosphate, 3H-uridine, or 3H-thymidine. After infection, the redistribution of each label among the different fractions of host and parasite was quantitatively determined and compared. There were no signs of accelerated degradation of host nucleic acid as the consequence of meningopneumonitis infection. Comparison of the specific activities of the meningopneumonitis nucleic acids with that of the acid-soluble fraction of host cell cytoplasm suggested that the major source of precursors for parasite nucleic acid synthesis was the common cytoplasmic pool of the infected host cell.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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