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. 1985 Nov;56(2):600–606. doi: 10.1128/jvi.56.2.600-606.1985

Transcription mapping of the varicella-zoster virus genome.

J M Ostrove, W Reinhold, C M Fan, S Zorn, J Hay, S E Straus
PMCID: PMC252617  PMID: 2997479

Abstract

RNA was isolated from varicella-zoster virus-infected Flow 5000 cells (diploid fibroblasts) at late times after infection. With the use of overlapping DNA probes representing all regions of the varicella-zoster genome, an extensive Northern blot analysis of the RNA was carried out. The analysis revealed at least 58 discrete transcripts ranging in size from approximately 0.8 to 6.5 kilobases. RNAs were found to be homologous to all probes used except for those mapping at approximately map unit 0.3, where no RNA transcripts could be detected. Comparison of the sizes and locations of RNA transcripts mapping in the right-hand ends of the varicella-zoster virus and the herpes simplex virus DNAs shows a number of striking analogies, suggesting their similar genomic organization.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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