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. 2008 Sep;125(1):91–100. doi: 10.1111/j.1365-2567.2008.02824.x

Figure 3.

Figure 3

Dex MDC have reduced capacity to stimulate Th1 cytokine production but induce secretion of IL-10 by T-cells. (a) Relative IFN-γ production by predex and dex MDC compared to control-MDC on day 7. Supernatants of T cells stimulated by control MDC contained on average 456 ± 131 pg/ml IFN-γ. To exclude variations in absolute IFN-γ production between experiments, IFN-γ concentration in culture media of T cells stimulated with control MDC was normalized to 100%, thereby allowing easy pairwise comparison. Data represent mean with SEM of seven separate experiments. (b) Relative IL-2 production by control, predex and dex MDC on day 4. Supernatants of T cells stimulated by control MDC contained 260 ± 100 pg/ml IL-2. (c) Relative IL-10 production by control, predex and dex MDC on day 7. Supernatants of T cells stimulated by control MDC contained 10 ± 1·3 pg/ml IL-10. Data represent mean with SEM of six separate experiments. *P ≤ 0·03 for comparison of dex MDC versus control MDC.