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. 1985 Nov;56(2):647–650. doi: 10.1128/jvi.56.2.647-650.1985

Restriction endonuclease mapping of adenovirus 35, a type isolated from immunocompromised hosts.

G Valderrama-Leon, P Flomenberg, M S Horwitz
PMCID: PMC252627  PMID: 2997485

Abstract

The DNA of adenovirus 35 (Ad35), a type recently associated with infections in immunocompromised hosts, was mapped by the use of BamHI, SmaI, PstI, EcoRI, and HpaI restriction endonucleases. In addition to standard mapping procedures, we used the in vitro adenovirus DNA replication system with origins at both physical ends of the linear molecule to determine the terminal fragments. Deletions of single restriction endonuclease sites in a group of closely related adenovirus isolates from patients with acquired immunodeficiency syndrome helped determine the location of some DNA fragments on the genome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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