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. 1985 Nov;56(2):651–654. doi: 10.1128/jvi.56.2.651-654.1985

Group B coxsackieviruses readily establish persistent infections in human lymphoid cell lines.

D Matteucci, M Paglianti, A M Giangregorio, M R Capobianchi, F Dianzani, M Bendinelli
PMCID: PMC252628  PMID: 2997486

Abstract

Exposing human lymphoid cell lines to uncloned or recently cloned group B coxsackieviruses results in the frequent establishment of chronically infected cultures. Persistence is maintained by a carrier culture mechanism involving virus spread through the medium and replication among a minority of cells at any given time. These studies provide a model for persistence by highly cytocidal viruses.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ahmed R., Kauffman R. S., Fields B. N. Genetic variation during persistent reovirus infection: isolation of cold-sensitive and temperature-sensitive mutants from persistently infected L cells. Virology. 1983 Nov;131(1):71–78. doi: 10.1016/0042-6822(83)90534-2. [DOI] [PubMed] [Google Scholar]
  2. Andiman W. A., Miller G. Persistent infection with adenovirus types 5 and 6 in lymphoid cells from humans and woolly monkeys. J Infect Dis. 1982 Jan;145(1):83–88. doi: 10.1093/infdis/145.1.83. [DOI] [PubMed] [Google Scholar]
  3. Bendinelli M., Matteucci D., Toniolo A., Patanè A. M., Pistillo M. P. Impairment of immunocompetent mouse spleen cell functions by infection with coxsackievirus B3. J Infect Dis. 1982 Dec;146(6):797–805. doi: 10.1093/infdis/146.6.797. [DOI] [PubMed] [Google Scholar]
  4. Carp R. I. Persistent infection of human lymphoid cells with poliovirus and development of temperature-sensitive mutants. Intervirology. 1981;15(1):49–56. doi: 10.1159/000149214. [DOI] [PubMed] [Google Scholar]
  5. Creager R. S., Cardamone J. J., Jr, Youngner J. S. Human lymphoblastoid cell lines of B- and T-cell origin: different responses to infection with vesicular stomatitis virus. Virology. 1981 May;111(1):211–222. doi: 10.1016/0042-6822(81)90666-8. [DOI] [PubMed] [Google Scholar]
  6. Creager R. S., Whitaker-Dowling P., Frey T. K., Youngner J. S. Varied responses of human B-lymphoblastoid cell lines to infection with vesicular stomatitis virus. Virology. 1982 Sep;121(2):414–419. doi: 10.1016/0042-6822(82)90179-9. [DOI] [PubMed] [Google Scholar]
  7. Cummings P. J., Lakomy R. J., Rinaldo C. R., Jr Characterization of herpes simplex virus persistence in a human T lymphoblastoid cell line. Infect Immun. 1981 Dec;34(3):817–827. doi: 10.1128/iai.34.3.817-827.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Damonte E. B., Mersich S. E., Coto C. E. Response of cells persistently infected with arenaviruses to superinfection with homotypic and heterotypic viruses. Virology. 1983 Sep;129(2):474–478. doi: 10.1016/0042-6822(83)90185-x. [DOI] [PubMed] [Google Scholar]
  9. Friedman R. M., Ramseur J. M. Mechanisms of persistent infections by cytopathic viruses in tissue culture. Brief review. Arch Virol. 1979;60(2):83–103. doi: 10.1007/BF01348025. [DOI] [PubMed] [Google Scholar]
  10. Holland J., Spindler K., Horodyski F., Grabau E., Nichol S., VandePol S. Rapid evolution of RNA genomes. Science. 1982 Mar 26;215(4540):1577–1585. doi: 10.1126/science.7041255. [DOI] [PubMed] [Google Scholar]
  11. Ju G., Udem S., Rager-Zisman B., Bloom B. R. Isolation of a heterogeneous population of temperature-sensitive mutants of measles virus from persistently infected human lymphoblastoid cell lines. J Exp Med. 1978 Jun 1;147(6):1637–1652. doi: 10.1084/jem.147.6.1637. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Lipton H. L. Persistent Theiler's murine encephalomyelitis virus infection in mice depends on plaque size. J Gen Virol. 1980 Jan;46(1):169–177. doi: 10.1099/0022-1317-46-1-169. [DOI] [PubMed] [Google Scholar]
  13. MACPHERSON I., MONTAGNIER L. AGAR SUSPENSION CULTURE FOR THE SELECTIVE ASSAY OF CELLS TRANSFORMED BY POLYOMA VIRUS. Virology. 1964 Jun;23:291–294. doi: 10.1016/0042-6822(64)90301-0. [DOI] [PubMed] [Google Scholar]
  14. Matteucci D., Toniolo A., Conaldi P. G., Basolo F., Gori Z., Bendinelli M. Systemic lymphoid atrophy in coxsackievirus B3-infected mice: effects of virus and immunopotentiating agents. J Infect Dis. 1985 Jun;151(6):1100–1108. doi: 10.1093/infdis/151.6.1100. [DOI] [PubMed] [Google Scholar]
  15. Meinkoth J., Kennedy S. I. Semliki forest virus persistence in mouse L929 cells. Virology. 1980 Jan 15;100(1):141–155. doi: 10.1016/0042-6822(80)90560-7. [DOI] [PubMed] [Google Scholar]
  16. Miller J. R. Prolonged intracerebral infection with poliovirus in asymptomatic mice. Ann Neurol. 1981 Jun;9(6):590–596. doi: 10.1002/ana.410090613. [DOI] [PubMed] [Google Scholar]
  17. Nilsson K., Klein G. Phenotypic and cytogenetic characteristics of human B-lymphoid cell lines and their relevance for the etiology of Burkitt's lymphoma. Adv Cancer Res. 1982;37:319–380. doi: 10.1016/s0065-230x(08)60886-6. [DOI] [PubMed] [Google Scholar]

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