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. 1985 Dec;56(3):1041–1044. doi: 10.1128/jvi.56.3.1041-1044.1985

Novel 2',5'-oligoadenylates synthesized in interferon-treated, vaccinia virus-infected cells.

A P Rice, S M Kerr, W K Roberts, R E Brown, I M Kerr
PMCID: PMC252683  PMID: 2415713

Abstract

2-5A[ppp(A2'p)nA] and related materials accumulate to greater than micromolar concentrations in vaccinia virus-infected HeLa cells and in interferon-treated, vaccinia-infected HeLa, CV1, and L929 cells even when virus replication is not inhibited. A variably complex mixture of authentic 2-5A (n = 2 to 4), nonphosphorylated cores [(A2'p)nA; n = 2 to 5], and additional compounds of unknown structure was observed.

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Selected References

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