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. 1986 Feb;57(2):674–677. doi: 10.1128/jvi.57.2.674-677.1986

Structure of a cloned circular retroviral DNA containing a tRNA sequence between the terminal repeats.

J Colicelli, S P Goff
PMCID: PMC252783  PMID: 2418216

Abstract

In the course of analyzing a series of cloned circular retroviral DNAs, we recovered an unusual clone. The molecule consisted of a complete viral genome containing two copies of the long terminal repeat with extra sequences between the repeats. These extra bases proved to be a nearly complete DNA copy of a glycine tRNA, including bases that corresponded to modified and nonpairing bases of the mature tRNA. A model is proposed to account for the formation of the aberrant clone.

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Selected References

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