Skip to main content
PMC home page
Journal of Virology logoLink to Journal of Virology
. 1986 Feb;57(2):697–700. doi: 10.1128/jvi.57.2.697-700.1986

Characterization of a gene coding for M proteins which is involved in host range restriction of an avian influenza A virus in monkeys.

A J Buckler-White, C W Naeve, B R Murphy
PMCID: PMC252788  PMID: 3080604

Abstract

The nucleotide sequence of the region of RNA segment 7 coding for the M1 and M2 proteins of avian influenza A/Mallard/New York/6750/78 was determined, and the deduced amino acid sequences were compared to other avian and human M protein sequences. The M2 proteins of the avian and human viruses have diverged much more than the M1 proteins, although amino acids specific for avian and human viruses were found in both M1 and M2 proteins.

Full text

PDF
697

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allen H., McCauley J., Waterfield M., Gething M. J. Influenza virus RNA segment 7 has the coding capacity for two polypeptides. Virology. 1980 Dec;107(2):548–551. doi: 10.1016/0042-6822(80)90324-4. [DOI] [PubMed] [Google Scholar]
  2. Bean W. J. Correlation of influenza A virus nucleoprotein genes with host species. Virology. 1984 Mar;133(2):438–442. doi: 10.1016/0042-6822(84)90410-0. [DOI] [PubMed] [Google Scholar]
  3. Massicot J. G., Murphy B. R., Thierry F., Markoff L., Huang K. Y., Chanock R. M. Temperature-sensitive mutants of influenza virus. Identification of the loci of the two ts lesions in the Udorn-ts-1A2 donor virus and the correlation of the presence of these two ts lesions with a predictable level of attenuation. Virology. 1980 Feb;101(1):242–249. doi: 10.1016/0042-6822(80)90499-7. [DOI] [PubMed] [Google Scholar]
  4. McCauley J. W., Mahy B. W., Inglis S. C. Nucleotide sequence of fowl plague virus RNA segment 7. J Gen Virol. 1982 Jan;58(Pt 1):211–215. doi: 10.1099/0022-1317-58-1-211. [DOI] [PubMed] [Google Scholar]
  5. Murphy B. R., Buckler-White A. J., London W. T., Harper J., Tierney E. L., Miller N. T., Reck L. J., Chanock R. M., Hinshaw V. S. Avian-human reassortant influenza A viruses derived by mating avian and human influenza A viruses. J Infect Dis. 1984 Dec;150(6):841–850. doi: 10.1093/infdis/150.6.841. [DOI] [PubMed] [Google Scholar]
  6. Murphy B. R., Sly D. L., Tierney E. L., Hosier N. T., Massicot J. G., London W. T., Chanock R. M., Webster R. G., Hinshaw V. S. Reassortant virus derived from avian and human influenza A viruses is attenuated and immunogenic in monkeys. Science. 1982 Dec 24;218(4579):1330–1332. doi: 10.1126/science.6183749. [DOI] [PubMed] [Google Scholar]
  7. Naeve C. W., Hinshaw V. S., Webster R. G. Mutations in the hemagglutinin receptor-binding site can change the biological properties of an influenza virus. J Virol. 1984 Aug;51(2):567–569. doi: 10.1128/jvi.51.2.567-569.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Ortín J., Martínez C., del Río L., Dávila M., López-Galíndez C., Villanueva N., Domingo E. Evolution of the nucleotide sequence of influenza virus RNA segment 7 during drift of the H3N2 subtype. Gene. 1983 Aug;23(2):233–239. doi: 10.1016/0378-1119(83)90055-0. [DOI] [PubMed] [Google Scholar]
  9. Robertson J. S. 5' and 3' terminal nucleotide sequences of the RNA genome segments of influenza virus. Nucleic Acids Res. 1979 Aug 24;6(12):3745–3757. doi: 10.1093/nar/6.12.3745. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Sanger F., Nicklen S., Coulson A. R. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463–5467. doi: 10.1073/pnas.74.12.5463. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Skehel J. J., Hay A. J. Nucleotide sequences at the 5' termini of influenza virus RNAs and their transcripts. Nucleic Acids Res. 1978 Apr;5(4):1207–1219. doi: 10.1093/nar/5.4.1207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Tian S. F., Buckler-White A. J., London W. T., Reck L. J., Chanock R. M., Murphy B. R. Nucleoprotein and membrane protein genes are associated with restriction of replication of influenza A/Mallard/NY/78 virus and its reassortants in squirrel monkey respiratory tract. J Virol. 1985 Mar;53(3):771–775. doi: 10.1128/jvi.53.3.771-775.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Winter G., Fields S. Cloning of influenza cDNA ino M13: the sequence of the RNA segment encoding the A/PR/8/34 matrix protein. Nucleic Acids Res. 1980 May 10;8(9):1965–1974. doi: 10.1093/nar/8.9.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES