Abstract
AIM: To measure total energy expenditure and body composition in small for gestational age (SGA) infants in order to investigate proposed hypermetabolism in such babies. METHODS: A cross sectional study of 52 SGA infants measured at 5 weeks of age was made, using existing data from appropriate for gestational age (AGA) infants as controls. The double labelled water technique was used to assess both total energy expenditure and body composition. RESULTS: Multiple regression analysis showed that expressing energy expenditure per kg fat free mass adjusts for body composition in infants of this age. The relation between total energy expenditure and fat free mass differed between the two groups. CONCLUSION: These data indicate that for a given fat free mass the total energy expenditure of SGA infants is greater than that of AGA infants. Such data should be taken into account when energy requirements for SGA infants are being considered.
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- Abdulrazzaq Y. M., Brooke O. G. Is the raised metabolic rate of the small for gestation infant due to his relatively large brain size. Early Hum Dev. 1988 Mar;16(2-3):253–261. doi: 10.1016/0378-3782(88)90106-5. [DOI] [PubMed] [Google Scholar]
- Bhakoo O. N., Scopes J. W. Minimal rates of oxygen consumption in small-for-dates babies during the first week of life. Arch Dis Child. 1974 Jul;49(7):583–585. doi: 10.1136/adc.49.7.583. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brooke O. G., Wood C., Butters F. The body proportions for small-for-dates infants. Early Hum Dev. 1984 Sep;10(1-2):85–94. doi: 10.1016/0378-3782(84)90114-2. [DOI] [PubMed] [Google Scholar]
- Cauderay M., Schutz Y., Micheli J. L., Calame A., Jéquier E. Energy-nitrogen balances and protein turnover in small and appropriate for gestational age low birthweight infants. Eur J Clin Nutr. 1988 Feb;42(2):125–136. [PubMed] [Google Scholar]
- Chessex P., Reichman B., Verellen G., Putet G., Smith J. M., Heim T., Swyer P. R. Metabolic consequences of intrauterine growth retardation in very low birthweight infants. Pediatr Res. 1984 Aug;18(8):709–713. doi: 10.1203/00006450-198408000-00006. [DOI] [PubMed] [Google Scholar]
- Coward W. A., Roberts S. B., Cole T. J. Theoretical and practical considerations in the doubly-labelled water (2H2(18)O) method for the measurement of carbon dioxide production rate in man. Eur J Clin Nutr. 1988 Mar;42(3):207–212. [PubMed] [Google Scholar]
- Coward W. A. Stable isotopic methods for measuring energy expenditure. The doubly-labelled-water (2H2(18)O) method: principles and practice. Proc Nutr Soc. 1988 Sep;47(3):209–218. doi: 10.1079/pns19880037. [DOI] [PubMed] [Google Scholar]
- Davies P. S., Cole T. J., Lucas A. Adjusting energy expenditure for body weight in early infancy. Eur J Clin Nutr. 1989 Sep;43(9):641–645. [PubMed] [Google Scholar]
- Davies P. S. Energy metabolism and obesity in childhood. Horm Res. 1993;39 (Suppl 3):77–80. doi: 10.1159/000182789. [DOI] [PubMed] [Google Scholar]
- Davies P. S., Ewing G., Lucas A. Energy expenditure in early infancy. Br J Nutr. 1989 Nov;62(3):621–629. doi: 10.1079/bjn19890062. [DOI] [PubMed] [Google Scholar]
- Fomon S. J., Haschke F., Ziegler E. E., Nelson S. E. Body composition of reference children from birth to age 10 years. Am J Clin Nutr. 1982 May;35(5 Suppl):1169–1175. doi: 10.1093/ajcn/35.5.1169. [DOI] [PubMed] [Google Scholar]
- Hill J. R., Robinson D. C. Oxygen consumption in normally grown, small-for-dates and large-for-dates new-born infants. J Physiol. 1968 Dec;199(3):685–703. doi: 10.1113/jphysiol.1968.sp008673. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Owen O. E., Holup J. L., D'Alessio D. A., Craig E. S., Polansky M., Smalley K. J., Kavle E. C., Bushman M. C., Owen L. R., Mozzoli M. A. A reappraisal of the caloric requirements of men. Am J Clin Nutr. 1987 Dec;46(6):875–885. doi: 10.1093/ajcn/46.6.875. [DOI] [PubMed] [Google Scholar]
- Picaud J. C., Putet G., Rigo J., Salle B. L., Senterre J. Metabolic and energy balance in small- and appropriate-for-gestational-age, very low-birth-weight infants. Acta Paediatr Suppl. 1994 Dec;405:54–59. doi: 10.1111/j.1651-2227.1994.tb13399.x. [DOI] [PubMed] [Google Scholar]
- Ravussin E., Bogardus C. Relationship of genetics, age, and physical fitness to daily energy expenditure and fuel utilization. Am J Clin Nutr. 1989 May;49(5 Suppl):968–975. doi: 10.1093/ajcn/49.5.968. [DOI] [PubMed] [Google Scholar]
- Wells J. C., Davies P. S. Sleeping metabolic rate and body size in 12-week-old infants. Eur J Clin Nutr. 1995 May;49(5):323–328. [PubMed] [Google Scholar]