Skip to main content
Journal of Virology logoLink to Journal of Virology
. 1986 Mar;57(3):1173–1176. doi: 10.1128/jvi.57.3.1173-1176.1986

Papillomavirus DNA associated with pulmonary fibromatosis in European elks.

J Moreno-López, T Mörner, U Pettersson
PMCID: PMC252855  PMID: 3005617

Abstract

Multiple beadlike fibromas have been observed in the lungs of European elks bearing cutaneous fibromas and fibropapillomas. DNA extracted from the lung fibromas was found to contain multiple copies of unintegrated European elk papillomavirus DNA, indicating an association between pulmonary fibromatosis and papillomavirus. No virus particles were observed in the tumor tissue by electron microscopy. Histological examination revealed that the lung fibromas had a morphology similar to that of cutaneous fibromas.

Full text

PDF
1173

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Koller L. D., Olson C. Pulmonary fibroblastomas in a deer with cutaneous fibromatosis. Cancer Res. 1971 Oct;31(10):1373–1375. [PubMed] [Google Scholar]
  2. Miyake T., Kimura I., Ito Y. A semi-quantitative method for the formation of tumor nodules in rabbit lung: experiments with V times 2 carcinoma. Oncology. 1971;25(6):481–486. doi: 10.1159/000224598. [DOI] [PubMed] [Google Scholar]
  3. Moreno-Lopez J., Pettersson U., Dinter Z., Philipson L. Characterization of a papilloma virus from the European elk (EEPV). Virology. 1981 Jul 30;112(2):589–595. doi: 10.1016/0042-6822(81)90304-4. [DOI] [PubMed] [Google Scholar]
  4. Pfister H. Biology and biochemistry of papillomaviruses. Rev Physiol Biochem Pharmacol. 1984;99:111–181. doi: 10.1007/BFb0027716. [DOI] [PubMed] [Google Scholar]
  5. Robl M. G., Olson C. Oncogenic action of bovine papilloma virus in hamsters. Cancer Res. 1968 Aug;28(8):1596–1604. [PubMed] [Google Scholar]
  6. SYVERTON J. T. The pathogenesis of the rabbit papilloma-to-carcinoma sequence. Ann N Y Acad Sci. 1952 Jul 10;54(6):1126–1140. doi: 10.1111/j.1749-6632.1952.tb39983.x. [DOI] [PubMed] [Google Scholar]
  7. Southern E. M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975 Nov 5;98(3):503–517. doi: 10.1016/s0022-2836(75)80083-0. [DOI] [PubMed] [Google Scholar]
  8. Steffen D., Weinberg R. A. The integrated genome of murine leukemia virus. Cell. 1978 Nov;15(3):1003–1010. doi: 10.1016/0092-8674(78)90284-2. [DOI] [PubMed] [Google Scholar]
  9. Stenlund A., Moreno-Lopez J., Ahola H., Pettersson U. European elk papillomavirus: characterization of the genome, induction of tumors in animals, and transformation in vitro. J Virol. 1983 Nov;48(2):370–376. doi: 10.1128/jvi.48.2.370-376.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Stremlau A., Gissmann L., Ikenberg H., Stark M., Bannasch P., zur Hausen H. Human papillomavirus type 16 related DNA in an anaplastic carcinoma of the lung. Cancer. 1985 Apr 15;55(8):1737–1740. doi: 10.1002/1097-0142(19850415)55:8<1737::aid-cncr2820550820>3.0.co;2-o. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES