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. 1986 Jul;59(1):185–188. doi: 10.1128/jvi.59.1.185-188.1986

Human cytomegalovirus virion-associated protein with kinase activity.

W J Britt, D Auger
PMCID: PMC253057  PMID: 3012117

Abstract

Protein kinase activity was detected in immunoprecipitates of human cytomegalovirus virions and infected cells by using a monoclonal antibody directed against an abundant 68,000-dalton virion structural protein. Purification of this protein by electrophoresis confirmed that the kinase activity was associated with this protein. The kinase activity was dependent on divalent cations (Mg2+, Mn2+) and cyclic nucleotide independent and exhibited optimal activity at pH 7 to 8. The kinase phosphorylated threonine and serine but not tyrosine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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