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. 1986 Sep;59(3):735–739. doi: 10.1128/jvi.59.3.735-739.1986

Enhanced susceptibility to cytotoxic T lymphocytes of target cells isolated from virus-infected or interferon-treated mice.

J F Bukowski, R M Welsh
PMCID: PMC253251  PMID: 3488417

Abstract

Bone marrow cells and thymocytes isolated from virus-infected or interferon (IFN)-treated mice had marked increases in sensitivity to lysis by allospecific cytotoxic T lymphocytes (CTL) and in expression of class I histocompatibility antigens. Cultured fibroblasts treated with IFN in vitro yielded similar findings in addition to having increased sensitivity to lysis by virus-specific CTL. This indicates that virus-induced IFN may condition target cells in vivo for surveillance by CTL.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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