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. 2008 Jul 14;112(6):2353–2359. doi: 10.1182/blood-2008-03-147850

Figure 4.

Figure 4

shMRP4 down-regulates MRP4 protein and mRNA expression. MRP4 protein expression analyzed by immunocytochemistry in HEK-MRP4 cells transduced with pRetroSUPER.puro.vector (A, left; control) or pRetroSUPER.shMRP4.puro (A, right) or LC cultures from MUTZ3 stably transfected with pRetroSUPER.GFP.vector (B, left; control), or pRetroSUPER.GFP.shMRP4 (B, right). Original magnification, 100×. (C) Triplicate MRP4 mRNA levels measured by low-density array in MUTZ3-vector control (left) or MUTZ3-shMRP4 cells (right). Numbers indicate the fold increase (+) or decrease (−) with respect to MUTZ3-vector control levels (*P < .05).