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. 1986 Dec;60(3):1186–1191. doi: 10.1128/jvi.60.3.1186-1191.1986

Progressive reorganization of the host cell cytoskeleton during adenovirus infection.

M Staufenbiel, P Epple, W Deppert
PMCID: PMC253387  PMID: 3023671

Abstract

Infection of cells with adenovirus lead to a characteristic reorganization of all cytoskeleton systems, starting with alterations at the microtubuli of the cells. During this progress, the flat, extended, and polar morphology of the cytoskeleton became nonpolar and rounder. These rearrangements were initiated before the appearance of adenovirus structural proteins hexon and fiber, as well as before the shutoff of host protein synthesis. We conclude that these alterations reflect a specific reorganization rather than an unorganized breakdown of the cell during adenovirus infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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