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. 1988 Sep;62(9):3493–3496. doi: 10.1128/jvi.62.9.3493-3496.1988

Latent herpes simplex virus type 1 transcription in human trigeminal ganglia.

I Steiner 1, J G Spivack 1, D R O'Boyle 2nd 1, E Lavi 1, N W Fraser 1
PMCID: PMC253475  PMID: 2841498

Abstract

We studied latent herpes simplex virus type 1 gene expression in human trigeminal ganglia. Two transcripts were mapped to a 3.0-kilobase region within the long repeat region and appeared to be located in neuronal nuclei. These viral RNAs were not abundant during lytic replication and may represent an alternative pattern of herpes simplex virus type 1 gene expression involved in the pathogenesis of latent infection.

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Selected References

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