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. 1988 Dec;62(12):4752–4755. doi: 10.1128/jvi.62.12.4752-4755.1988

Integration of Friend murine leukemia virus into both alleles of the p53 oncogene in an erythroleukemic cell line.

G G Hicks 1, M Mowat 1
PMCID: PMC253591  PMID: 2846884

Abstract

The Friend virus-transformed erythroleukemic cell line DP16-9B4 has undergone a complex rearrangement of the p53 oncogene and lacks any detectable expression of the p53 protein. We report here characterization of both p53 alleles in this cell line and identify independent integrations of Friend murine leukemia virus sequences into the coding region of both alleles.

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Selected References

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