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. 1988 Dec;62(12):4809–4812. doi: 10.1128/jvi.62.12.4809-4812.1988

Helper-independent retrovirus vectors with Rous-associated virus type O long terminal repeats.

J J Greenhouse 1, C J Petropoulos 1, L B Crittenden 1, S H Hughes 1
PMCID: PMC253605  PMID: 2460645

Abstract

We have constructed nonpermuted replication-competent avian retrovirus vectors that derive from Rous sarcoma virus (S. H. Hughes, J. J. Greenhouse, C. J. Petropoulos, and P. Sutrave, J. Virol. 61:3004-3012, 1987). We describe here the construction and properties of corresponding vectors in which the long terminal repeats (LTRs) of the parental virus have been replaced by the LTRs of the endogenous chicken virus Rous-associated virus type O. The Rous-associated virus type O LTR vectors replicated approximately 1/10 as well as the parental vectors and expressed a test gene, chloramphenicol acetyltransferase, approximately 1/30 to 1/50 as well.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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