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Journal of the National Medical Association logoLink to Journal of the National Medical Association
. 1978 Oct;70(10):761–762.

Aspirin and Gastrointestinal Bleeding

John C Krantz Jr
PMCID: PMC2537102  PMID: 309511

Abstract

There is no other over-the-counter (OTC) drug having the widespread use of aspirin. Evoking the well-established analgesic, antipyretic, and anti-inflammatory activities with an amazingly low degree of toxicity, its use has increased in this country to the astounding figure of more than 20 tons daily. The observation that comparatively small daily doses of aspirin may serve as a means of preventing certain types of cardiovascular disasters may lead to even more widespread use of the drug. The most frequent untoward side effect of aspirin is gastric discomfort with or without microbleeding. The amount of bleeding is usually quite small but owing to the long interest of the author in buffered aspirin, it is prudent to determine whether or not this action of aspirin is serious.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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