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letter
. 1979 Mar;71(3):251–255.

Respiratory Effects of a Single, Moderately Acute, Smoke Inhalation Episode

Jairaj Prashad, Roscoe C Young Jr, Horace C Laster, Robert L Hackney Jr
PMCID: PMC2537360  PMID: 439155

Abstract

Twenty-three hospital employees who suffered ill effects of smoke inhalation were pulmonary-function tested within 72 hours, after ten weeks, and again after 45 weeks of exposure. Four nonexposed control subjects were selected for comparison of data.

Exposed persons commonly had restrictive lung disease which may have resulted from stimulation of irritant receptors in bronchi and/or interstitial edema of chemical injury at the level of the ventilation-perfusion unit. Airways obstruction was infrequent, despite the possibility of inhalation of di-isocyanates, an intermediary product of burning polyurethane foam that may cause chemical asthma. Eye and constitutional symptoms were also frequent.

Clinical recovery was as a rule rapid and complete (within a week), but physiologic recovery was protracted (over 45 weeks in some cases). Most surprisingly, cigarette smoking and/or presence of cardiopulmonary disease did not contribute to morbidity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aub J. C., Pittman H., Brues A. M. THE PULMONARY COMPLICATIONS: A CLINICAL DESCRIPTION. Ann Surg. 1943 Jun;117(6):834–840. doi: 10.1097/00000658-194311760-00006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Beal D. D., Lambeth J. T., Conner G. H. Follow-up studies on patients treated with steroids following pulmonary thermal and acrid smoke injury. Laryngoscope. 1968 Mar;78(3):396–403. doi: 10.1288/00005537-196803000-00010. [DOI] [PubMed] [Google Scholar]
  3. CONNER E. H., DUBOIS A. B., COMROE J. H., Jr Acute chemical injury of the airway and lungs. Experience with six cases. Anesthesiology. 1962 Jul-Aug;23:538–547. doi: 10.1097/00000542-196207000-00013. [DOI] [PubMed] [Google Scholar]
  4. Charles J., Bernstein A., Jones B., Jones D. J., Edwards J. H., Seal R. M., Seaton A. Hypersensitivity pneumonitis after exposure to isocyanates. Thorax. 1976 Apr;31(2):127–136. doi: 10.1136/thx.31.2.127. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. DiVincenti F. C., Pruitt B. A., Jr, Reckler J. M. Inhalation injuries. J Trauma. 1971 Feb;11(2):109–117. doi: 10.1097/00005373-197102000-00002. [DOI] [PubMed] [Google Scholar]
  6. Dressler D. P., Skornik W. A., Kupersmith S. Corticosteroid treatment of experimental smoke inhalation. Ann Surg. 1976 Jan;183(1):46–52. doi: 10.1097/00000658-197601000-00010. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Dyer R. F., Esch V. H. Polyvinyl chloride toxicity in fires. Hydrogen chloride toxicity in fire fighters. JAMA. 1976 Jan 26;235(4):393–397. [PubMed] [Google Scholar]
  8. Eckhauser F. E., Billote J., Burke J. F., Quinby W. C. Tracheostomy complicating massive burn injury. A plea for conservatism. Am J Surg. 1974 Apr;127(4):418–423. doi: 10.1016/0002-9610(74)90290-6. [DOI] [PubMed] [Google Scholar]
  9. Garzon A. A., Seltzer B., Song I. C., Bromberg B. E., Karlson K. E. Respiratory mechanics in patients with inhalation burns. J Trauma. 1970 Jan;10(1):57–62. doi: 10.1097/00005373-197001000-00007. [DOI] [PubMed] [Google Scholar]
  10. Harrison H. N., Zikria B. A. Management of respiratory problems in burned patients. Mod Treat. 1967 Nov;4(6):1263–1281. [PubMed] [Google Scholar]
  11. Hunt J. L., Agee R. N., Pruitt B. A., Jr Fiberoptic bronchoscopy in acute inhalation injury. J Trauma. 1975 Aug;15(8):641–649. doi: 10.1097/00005373-197508000-00004. [DOI] [PubMed] [Google Scholar]
  12. KORY R. C., CALLAHAN R., BOREN H. G., SYNER J. C. The Veterans Administration-Army cooperative study of pulmonary function. I. Clinical spirometry in normal men. Am J Med. 1961 Feb;30:243–258. doi: 10.1016/0002-9343(61)90096-1. [DOI] [PubMed] [Google Scholar]
  13. Landa J., Avery W. G., Sackner M. A. Some physiologic observations in smoke inhalation. Chest. 1972 Jan;61(1):62–64. doi: 10.1378/chest.61.1.62. [DOI] [PubMed] [Google Scholar]
  14. Landa J., Avery W. G., Sackner M. A. Some physiologic observations in smoke inhalation. Chest. 1972 Jan;61(1):62–64. doi: 10.1378/chest.61.1.62. [DOI] [PubMed] [Google Scholar]
  15. Lloyd E. L., MacRae W. R. Respiratory tract damage in burns. Case reports and review of the literature. Br J Anaesth. 1971 Apr;43(4):365–379. doi: 10.1093/bja/43.4.365. [DOI] [PubMed] [Google Scholar]
  16. Moylan J. A., Jr, Wilmore D. W., Mouton D. E., Pruitt B. A., Jr Early diagnosis of inhalation injury using 133 xenon lung scan. Ann Surg. 1972 Oct;176(4):477–484. doi: 10.1097/00000658-197210000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. PHILLIPS A. W., TANNER J. W., COPE O. BURN THERAPY. IV. RESPIRATORY TRACT DAMAGE (AN ACCOUNT OF THE CLINICAL, X-RAY AND POSTMORTEM FINDINGS) AND THE MEANING OF RESTLESSNESS. Ann Surg. 1963 Nov;158:799–811. doi: 10.1097/00000658-196311000-00008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Petajan J. H., Voorhees K. J., Packham S. C., Baldwin R. C., Einhorn I. N., Grunnet M. L., Dinger B. G., Birky M. M. Extreme toxicity from combustion products of a fire-retarded polyurethane foam. Science. 1975 Feb 28;187(4178):742–744. doi: 10.1126/science.1114319. [DOI] [PubMed] [Google Scholar]
  19. Peters J. M., Murphy R. L. Hazards to health: do it yourself polyurethane foam. Am Rev Respir Dis. 1971 Sep;104(3):432–433. doi: 10.1164/arrd.1971.104.3.432. [DOI] [PubMed] [Google Scholar]
  20. Petroff P. A., Hander E. W., Clayton W. H., Pruitt B. A. Pulmonary function studies after smoke inhalation. Am J Surg. 1976 Sep;132(3):346–351. doi: 10.1016/0002-9610(76)90391-3. [DOI] [PubMed] [Google Scholar]
  21. Pruitt B. A., Jr, Flemma R. J., DiVincenti F. C., Foley F. D., Mason A. D., Jr, Young W. G., Jr Pulmonary complications in burn patients. A comparative study of 697 patients. J Thorac Cardiovasc Surg. 1970 Jan;59(1):7–20. [PubMed] [Google Scholar]
  22. Sidor R., Peters J. M. Prevalence rates of chronic non-specific respiratory disease in fire fighters. Am Rev Respir Dis. 1974 Feb;109(2):255–261. doi: 10.1164/arrd.1974.109.2.255. [DOI] [PubMed] [Google Scholar]
  23. Stone H. H., Rhame D. W., Corbitt J. D., Given K. S., Martin J. D., Jr Respiratory burns: a correlation of clinical and laboratory results. Ann Surg. 1967 Feb;165(2):157–168. doi: 10.1097/00000658-196702000-00001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Wanner A., Cutchavaree A. Early recognition of upper airway obstruction following smoke inhalation. Am Rev Respir Dis. 1973 Dec;108(6):1421–1423. doi: 10.1164/arrd.1973.108.6.1421. [DOI] [PubMed] [Google Scholar]
  25. Webster J. R., McCabe M. M., Karp M. Recognition and management of smoke inhalation. JAMA. 1967 Jul 31;201(5):287–290. [PubMed] [Google Scholar]

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